Oestrogen as a calcium channel blocker

P. Collins, C. M. Beale, G. M C Rosano

Research output: Contribution to journalArticlepeer-review

Abstract

This paper reviews the evidence for calcium-antagonist properties of oestrogen which may offer long-term protective effects on the cardiovascular system in postmenopausal women. Oestrogen has already been shown to have a beneficial effect on cholesterol metabolism and deposition, thereby inhibiting the formation of atherosclerotic plaque and coronary atheroma. Calcium antagonism, resulting in both acute and chronic modulation of coronary and peripheral vasomotion, is another mechanism by which oestrogens may provide cardiovascular benefits to women, including those with existing cardiovascular disease.

Original languageEnglish
Pages (from-to)27-31
Number of pages5
JournalEuropean Heart Journal
Volume17
Issue numberSUPPL. D
Publication statusPublished - 1996

Keywords

  • Atherosclerosis
  • Calcium antagonism
  • Cardiovascular disease
  • Myocardial ischaemia
  • Oestrogen replacement therapy
  • Post-menopausal women

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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