Oestrogens and obesity as risk factors for endometrial cancer in Italy

C. la Vecchia, S. Franceschi, G. Gallus, A. Decarli, E. Colombo, C. Mangioni, G. Tognoni

Research output: Contribution to journalArticle

75 Citations (Scopus)

Abstract

In a case-control study to evaluate risk factors for endometrial cancer, obesity, history of various diseases, reproductive and menstrual characteristics, marital status, education, and lifetime use of female hormones were examined in 173 histologically proven endometrial cancers and 347 controls. Obesity, non-contraceptive oestrogen use, late menopause, low parity and history of uterine fibromyomas were associated with an increased risk of endometrial cancer. The relative risks of obesity and oestrogen use seem to fit well for an additive model. Histological differentiation was positively correlated both to oestrogen use and to level of overweight, supporting the hypothesis of a specific role of oestrogens in endometrial cancer.

Original languageEnglish
Pages (from-to)120-126
Number of pages7
JournalInternational Journal of Epidemiology
Volume11
Issue number2
Publication statusPublished - 1982

Fingerprint

Estrogen
Obesity
Risk Factors
Endometrial Neoplasms
Italy
Cancer
Estrogens
Additive Models
Case-control Study
Relative Risk
Hormones
Marital Status
Leiomyoma
Menopause
Parity
Case-Control Studies
Lifetime
Education
Risk factors
Evaluate

ASJC Scopus subject areas

  • Epidemiology
  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Reproductive Medicine
  • Obstetrics and Gynaecology

Cite this

la Vecchia, C., Franceschi, S., Gallus, G., Decarli, A., Colombo, E., Mangioni, C., & Tognoni, G. (1982). Oestrogens and obesity as risk factors for endometrial cancer in Italy. International Journal of Epidemiology, 11(2), 120-126.

Oestrogens and obesity as risk factors for endometrial cancer in Italy. / la Vecchia, C.; Franceschi, S.; Gallus, G.; Decarli, A.; Colombo, E.; Mangioni, C.; Tognoni, G.

In: International Journal of Epidemiology, Vol. 11, No. 2, 1982, p. 120-126.

Research output: Contribution to journalArticle

la Vecchia, C, Franceschi, S, Gallus, G, Decarli, A, Colombo, E, Mangioni, C & Tognoni, G 1982, 'Oestrogens and obesity as risk factors for endometrial cancer in Italy', International Journal of Epidemiology, vol. 11, no. 2, pp. 120-126.
la Vecchia C, Franceschi S, Gallus G, Decarli A, Colombo E, Mangioni C et al. Oestrogens and obesity as risk factors for endometrial cancer in Italy. International Journal of Epidemiology. 1982;11(2):120-126.
la Vecchia, C. ; Franceschi, S. ; Gallus, G. ; Decarli, A. ; Colombo, E. ; Mangioni, C. ; Tognoni, G. / Oestrogens and obesity as risk factors for endometrial cancer in Italy. In: International Journal of Epidemiology. 1982 ; Vol. 11, No. 2. pp. 120-126.
@article{264daf00c5e04e1a88f84d549db635bc,
title = "Oestrogens and obesity as risk factors for endometrial cancer in Italy",
abstract = "In a case-control study to evaluate risk factors for endometrial cancer, obesity, history of various diseases, reproductive and menstrual characteristics, marital status, education, and lifetime use of female hormones were examined in 173 histologically proven endometrial cancers and 347 controls. Obesity, non-contraceptive oestrogen use, late menopause, low parity and history of uterine fibromyomas were associated with an increased risk of endometrial cancer. The relative risks of obesity and oestrogen use seem to fit well for an additive model. Histological differentiation was positively correlated both to oestrogen use and to level of overweight, supporting the hypothesis of a specific role of oestrogens in endometrial cancer.",
author = "{la Vecchia}, C. and S. Franceschi and G. Gallus and A. Decarli and E. Colombo and C. Mangioni and G. Tognoni",
year = "1982",
language = "English",
volume = "11",
pages = "120--126",
journal = "International Journal of Epidemiology",
issn = "0300-5771",
publisher = "Oxford University Press",
number = "2",

}

TY - JOUR

T1 - Oestrogens and obesity as risk factors for endometrial cancer in Italy

AU - la Vecchia, C.

AU - Franceschi, S.

AU - Gallus, G.

AU - Decarli, A.

AU - Colombo, E.

AU - Mangioni, C.

AU - Tognoni, G.

PY - 1982

Y1 - 1982

N2 - In a case-control study to evaluate risk factors for endometrial cancer, obesity, history of various diseases, reproductive and menstrual characteristics, marital status, education, and lifetime use of female hormones were examined in 173 histologically proven endometrial cancers and 347 controls. Obesity, non-contraceptive oestrogen use, late menopause, low parity and history of uterine fibromyomas were associated with an increased risk of endometrial cancer. The relative risks of obesity and oestrogen use seem to fit well for an additive model. Histological differentiation was positively correlated both to oestrogen use and to level of overweight, supporting the hypothesis of a specific role of oestrogens in endometrial cancer.

AB - In a case-control study to evaluate risk factors for endometrial cancer, obesity, history of various diseases, reproductive and menstrual characteristics, marital status, education, and lifetime use of female hormones were examined in 173 histologically proven endometrial cancers and 347 controls. Obesity, non-contraceptive oestrogen use, late menopause, low parity and history of uterine fibromyomas were associated with an increased risk of endometrial cancer. The relative risks of obesity and oestrogen use seem to fit well for an additive model. Histological differentiation was positively correlated both to oestrogen use and to level of overweight, supporting the hypothesis of a specific role of oestrogens in endometrial cancer.

UR - http://www.scopus.com/inward/record.url?scp=0019949793&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019949793&partnerID=8YFLogxK

M3 - Article

VL - 11

SP - 120

EP - 126

JO - International Journal of Epidemiology

JF - International Journal of Epidemiology

SN - 0300-5771

IS - 2

ER -