Abstract
Four cases of chronic T lymphocytic leukaemia are characterized by selected monoclonal antibody combinations and double-fluorescence studies. We found 3 possible combinations: OKT4++ Leu8++ Leu9+, OKT4++ Leu8+ Leu9- and the OKT4++ Leu9++ Leu8- phentotypes are correlated with different biological aspects of the disease. No markers of T cell activation were found, and serological examinations did not reveal anti-HTLV-I antibodies. In considering a larger number of patients, multiparametric analysis could be useful to better classify this heterogeneous type of leukaemia.
| Original language | English |
|---|---|
| Pages (from-to) | 89-91 |
| Number of pages | 3 |
| Journal | Acta Haematologica |
| Volume | 75 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1986 |
Keywords
- Double-labelling studies
- Lymphocytes
- T lymphocytic leukaemia, chronic
ASJC Scopus subject areas
- Hematology
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De Paoli, P., Reitano, M., Battistin, S., Molaro, G., & Santini, G. (1986). OKT4+ chronic lymphocytic leukaemia cells display different reactivity with selected monoclonal antibody combinations. Acta Haematologica, 75(2), 89-91. https://doi.org/10.1159/000206092