Old and new targets for innovative antimalarial compounds

the different strategies of the Italian Malaria Network.

N. Basilico, E. Bosisio, F. Buelli, G. Campiani, M. Casagrande, F. Castelli, P. Coghi, Y. Corbett, L. Cortelezzi, S. D'Alessandro, M. Dell'Agli, F. Esposito, C. Fattorusso, E. Fattorusso, S. Finaurini, G. V. Galli, S. Gemma, A. Habluetzel, L. Lucantoni, S. Melato & 15 others D. Monti, P. Olliaro, F. Omodeo-Salè, S. Parapini, M. Persico, M. Rizzi, S. Romeo, F. Rossi, C. Rusconi, A. Sparatore, O. Taglialatela Scafati, E. van den Bogaart, D. Taramelli, N. Vaiana, S. Yerbanga

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Clinical treatment-failures to affordable drugs encouraged new investigation for discovery and development of new prophylactic and therapeutic interventions against malaria. The Drug Discovery Cluster (DDcl) of the Italian Malaria Network gathers several highly integrated and complementary laboratories from different Italian Institutions to identify, synthesise, screen in vitro and in vivo new antimalarial molecules directed against the intraerythrocytic stage of P. falciparum parasites and/or with transmission blocking activity to select lead compounds for further development. Complementary research activities, both in vitro and in the clinics, aim at investigating the pathogenetic mechanisms of severe malaria anaemia and the different manifestations of the disease in malaria-HIV co-infected patients to identify new therapies and improve survival.

Original languageEnglish
Pages (from-to)133-136
Number of pages4
JournalParassitologia
Volume50
Issue number1-2
Publication statusPublished - Jun 2008

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Antimalarials
Malaria
Drug Discovery
Treatment Failure
Anemia
Parasites
HIV
Survival
Therapeutics
Research
Pharmaceutical Preparations
In Vitro Techniques

ASJC Scopus subject areas

  • Parasitology

Cite this

Basilico, N., Bosisio, E., Buelli, F., Campiani, G., Casagrande, M., Castelli, F., ... Yerbanga, S. (2008). Old and new targets for innovative antimalarial compounds: the different strategies of the Italian Malaria Network. Parassitologia, 50(1-2), 133-136.

Old and new targets for innovative antimalarial compounds : the different strategies of the Italian Malaria Network. / Basilico, N.; Bosisio, E.; Buelli, F.; Campiani, G.; Casagrande, M.; Castelli, F.; Coghi, P.; Corbett, Y.; Cortelezzi, L.; D'Alessandro, S.; Dell'Agli, M.; Esposito, F.; Fattorusso, C.; Fattorusso, E.; Finaurini, S.; Galli, G. V.; Gemma, S.; Habluetzel, A.; Lucantoni, L.; Melato, S.; Monti, D.; Olliaro, P.; Omodeo-Salè, F.; Parapini, S.; Persico, M.; Rizzi, M.; Romeo, S.; Rossi, F.; Rusconi, C.; Sparatore, A.; Scafati, O. Taglialatela; van den Bogaart, E.; Taramelli, D.; Vaiana, N.; Yerbanga, S.

In: Parassitologia, Vol. 50, No. 1-2, 06.2008, p. 133-136.

Research output: Contribution to journalArticle

Basilico, N, Bosisio, E, Buelli, F, Campiani, G, Casagrande, M, Castelli, F, Coghi, P, Corbett, Y, Cortelezzi, L, D'Alessandro, S, Dell'Agli, M, Esposito, F, Fattorusso, C, Fattorusso, E, Finaurini, S, Galli, GV, Gemma, S, Habluetzel, A, Lucantoni, L, Melato, S, Monti, D, Olliaro, P, Omodeo-Salè, F, Parapini, S, Persico, M, Rizzi, M, Romeo, S, Rossi, F, Rusconi, C, Sparatore, A, Scafati, OT, van den Bogaart, E, Taramelli, D, Vaiana, N & Yerbanga, S 2008, 'Old and new targets for innovative antimalarial compounds: the different strategies of the Italian Malaria Network.', Parassitologia, vol. 50, no. 1-2, pp. 133-136.
Basilico N, Bosisio E, Buelli F, Campiani G, Casagrande M, Castelli F et al. Old and new targets for innovative antimalarial compounds: the different strategies of the Italian Malaria Network. Parassitologia. 2008 Jun;50(1-2):133-136.
Basilico, N. ; Bosisio, E. ; Buelli, F. ; Campiani, G. ; Casagrande, M. ; Castelli, F. ; Coghi, P. ; Corbett, Y. ; Cortelezzi, L. ; D'Alessandro, S. ; Dell'Agli, M. ; Esposito, F. ; Fattorusso, C. ; Fattorusso, E. ; Finaurini, S. ; Galli, G. V. ; Gemma, S. ; Habluetzel, A. ; Lucantoni, L. ; Melato, S. ; Monti, D. ; Olliaro, P. ; Omodeo-Salè, F. ; Parapini, S. ; Persico, M. ; Rizzi, M. ; Romeo, S. ; Rossi, F. ; Rusconi, C. ; Sparatore, A. ; Scafati, O. Taglialatela ; van den Bogaart, E. ; Taramelli, D. ; Vaiana, N. ; Yerbanga, S. / Old and new targets for innovative antimalarial compounds : the different strategies of the Italian Malaria Network. In: Parassitologia. 2008 ; Vol. 50, No. 1-2. pp. 133-136.
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