Abstract
The introduction of new rapid diagnostic tools for tuberculosis (TB) and the promising TB drugs pipeline together with the development of a new World Health Organization Strategy post 2015 allows new discussions on how to direct TB control. The European Respiratory Society's European Forum for TB Innovation was created to stimulate discussion on how to best take advantage of old and new opportunities, and advances, to improve TB control and eventually progress towards the elimination of TB. While TB control is aimed at reducing the incidence of TB by early diagnosis and treatment of infectious cases of TB, TB elimination requires focus on sterilising the pool of latently infected individuals, from which future TB cases would be generated. This manuscript describes the three core components that are necessary to implement the elimination strategy fully. 1) Improve diagnosis of latent TB infected individuals. 2) Improve regimens to treat latent TB infection. 3) ensure public health commitment to make both 1) and 2) possible. Old and new evidence is critically described, focusing on the European commitment to reach elimination and on the innovative experiences and best practices available.
| Original language | English |
|---|---|
| Pages (from-to) | 785-801 |
| Number of pages | 17 |
| Journal | European Respiratory Journal |
| Volume | 42 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Sep 1 2013 |
Fingerprint
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
Cite this
Old ideas to innovate tuberculosis control : Preventive treatment to achieve elimination. / Diel, Roland; Loddenkemper, Robert; Zellweger, Jean Pierre; Sotgiu, Giovanni; D'Ambrosio, Lia; Centis, Rosella; Van Der Werf, Marieke J.; Dara, Masoud; Detjen, Anne; Gondrie, Peter; Reichman, Lee; Blasi, Francesco; Migliori, Giovanni Battista.
In: European Respiratory Journal, Vol. 42, No. 3, 01.09.2013, p. 785-801.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Old ideas to innovate tuberculosis control
T2 - Preventive treatment to achieve elimination
AU - Diel, Roland
AU - Loddenkemper, Robert
AU - Zellweger, Jean Pierre
AU - Sotgiu, Giovanni
AU - D'Ambrosio, Lia
AU - Centis, Rosella
AU - Van Der Werf, Marieke J.
AU - Dara, Masoud
AU - Detjen, Anne
AU - Gondrie, Peter
AU - Reichman, Lee
AU - Blasi, Francesco
AU - Migliori, Giovanni Battista
PY - 2013/9/1
Y1 - 2013/9/1
N2 - The introduction of new rapid diagnostic tools for tuberculosis (TB) and the promising TB drugs pipeline together with the development of a new World Health Organization Strategy post 2015 allows new discussions on how to direct TB control. The European Respiratory Society's European Forum for TB Innovation was created to stimulate discussion on how to best take advantage of old and new opportunities, and advances, to improve TB control and eventually progress towards the elimination of TB. While TB control is aimed at reducing the incidence of TB by early diagnosis and treatment of infectious cases of TB, TB elimination requires focus on sterilising the pool of latently infected individuals, from which future TB cases would be generated. This manuscript describes the three core components that are necessary to implement the elimination strategy fully. 1) Improve diagnosis of latent TB infected individuals. 2) Improve regimens to treat latent TB infection. 3) ensure public health commitment to make both 1) and 2) possible. Old and new evidence is critically described, focusing on the European commitment to reach elimination and on the innovative experiences and best practices available.
AB - The introduction of new rapid diagnostic tools for tuberculosis (TB) and the promising TB drugs pipeline together with the development of a new World Health Organization Strategy post 2015 allows new discussions on how to direct TB control. The European Respiratory Society's European Forum for TB Innovation was created to stimulate discussion on how to best take advantage of old and new opportunities, and advances, to improve TB control and eventually progress towards the elimination of TB. While TB control is aimed at reducing the incidence of TB by early diagnosis and treatment of infectious cases of TB, TB elimination requires focus on sterilising the pool of latently infected individuals, from which future TB cases would be generated. This manuscript describes the three core components that are necessary to implement the elimination strategy fully. 1) Improve diagnosis of latent TB infected individuals. 2) Improve regimens to treat latent TB infection. 3) ensure public health commitment to make both 1) and 2) possible. Old and new evidence is critically described, focusing on the European commitment to reach elimination and on the innovative experiences and best practices available.
UR - http://www.scopus.com/inward/record.url?scp=84880142045&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84880142045&partnerID=8YFLogxK
U2 - 10.1183/09031936.00205512
DO - 10.1183/09031936.00205512
M3 - Article
VL - 42
SP - 785
EP - 801
JO - European Journal of Respiratory Diseases
JF - European Journal of Respiratory Diseases
SN - 0903-1936
IS - 3
ER -