Oligoclonal bands in Devic's neuromyelitis optica and multiple sclerosis: Differences in repeated cerebrospinal fluid examinations

Roberto Bergamaschi, S. Tonietti, D. Franciotta, E. Candeloro, E. Tavazzi, G. Piccolo, A. Romani, V. Cosi

Research output: Contribution to journalArticlepeer-review

Abstract

We studied repeated cerebrospinal fluids of patients with Devic's neuromyelitis optica (NMO) and multiple sclerosis (MS). Variations of oligoclonal bands (OBs) had opposite trends in the two groups. In MS, OBs were detected in 399 of 411 patients (97%) and never disappeared. In NMO, OBs were detected in three of 11 patients (27%) and always disappeared. The hypothesis that NMO and MS follow distinct pathogenetic pathways is supported by our findings, which can be useful for the differentiation of NMO from MS.

Original languageEnglish
Pages (from-to)2-4
Number of pages3
JournalMultiple Sclerosis Journal
Volume10
Issue number1
DOIs
Publication statusPublished - Feb 2004

Keywords

  • Cerebrospinal fluid
  • Devic's syndrome
  • Multiple sclerosis
  • Neuromyelitis optica
  • Oligoclonal bands

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint Dive into the research topics of 'Oligoclonal bands in Devic's neuromyelitis optica and multiple sclerosis: Differences in repeated cerebrospinal fluid examinations'. Together they form a unique fingerprint.

Cite this