Omeprazole vs. ranitidine in the short-term treatment of duodenal ulcer: An Italian multicenter study

L. Barbara, A. Blasi, R. Cheli, R. Corinaldesi, G. Dobrilla, A. Francavilla, M. Rinetti, P. Vezzaldini, R. Abbiati, R. Gradnik, G. Ciancamerla, F. Chilovi, M. Felder, M. Ingrosso, A. Mangiameli, A. Paternico, R. Sivelli, P. Tomassetti, G. Labo

Research output: Contribution to journalArticle

Abstract

A double-blind, double-dummy, randomized Italian multicenter trial was carried out to compare the efficacy and safety of omeprazole 20 mg in the morning and ranitidine 150 mg b.i.d. in short-term treatment of acute duodenal ulcer. One hundred and twenty-one patients (61 in the omeprazole and 60 in the ranitidine group) with endoscopically proven active duodenal ulcer, completed the study. The healing rates after 2, 4 and 6 weeks were 66, 97 and 100%, respectively, with omeprazole and 53, 85 and 92%, respectively, with ranitidine. The difference was statistically significant (p

Original languageEnglish
Pages (from-to)229-232
Number of pages4
JournalHepato-Gastroenterology
Volume34
Issue number5
Publication statusPublished - 1987

ASJC Scopus subject areas

  • Gastroenterology

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