OMERACT agreement and reliability study of ultrasonographic elementary lesions in osteoarthritis of the foot

Alen Zabotti, Georgios Filippou, Marco Canzoni, Antonella Adinolfi, Valentina Picerno, Greta Carrara, Peter Balint, George Bruyn, Maria Antonietta D'Agostino, Nemanja Damjanov, Andrea Delle Sedie, Emilio Filippucci, Maria Luz Gonzalez Fernandez, Hilde Berner Hammer, Zunaid Karim, Peter Mandl, Ingrid Moller, Maria Rosario Morales Lozano, Esperanza Naredo, Francesco PortaGarifallia Sakellariou, Lene Terslev, Carlo Alberto Scirè, Annamaria Iagnocco

Research output: Contribution to journalArticle

Abstract

Objective To evaluate the level of agreement on ultrasonographic (US) lesions among highly experienced sonographers as well as the intraobserver and interobserver reliability of inflammatory and structural US lesions in patients with osteoarthritis (OA) of the foot. Methods After a systematic literature review, a Delphi survey was performed to test definitions of US lesions in OA of the foot, including inflammatory lesions (ie, synovial hypertrophy [SH], joint effusion [JE], power Doppler signal [PD]), and structural abnormalities (ie, cartilage damage [CD] and osteophytes). Subsequently, the reliability of US in assessing the aforementioned lesions was tested on static images as well as during a live exercise. Reliability was assessed by kappa analyses and prevalence-adjusted bias-adjusted kappa (PABAK) on a dichotomous and an ordinal scale. Results Intraobserver and interobserver reliability for SH and JE evaluated by binary scoring was good for both components, while the intraobserver reliability for semiquantitative scoring of SH ranged from moderate in the web-based exercise (PABAK 0.49) to good (PABAK 0.8) in the live exercise. Reliability for CD and PD assessments were respectively good and excellent in all exercises (ranged from PABAK 0.61 to 0.79 for CD and 0.88 to 0.95 for PD). The interobserver reliability for the semiquantitative scoring of osteophytes was fair in the live exercise (PABAK 0.36) and moderate in the static exercise (PABAK 0.60). Conclusions Consensual US definitions were found to be reliable for assessing inflammatory lesions in OA of the foot, while the use of US to assess structural damage requires further studies.

Original languageEnglish
Article numbere000795
JournalRMD Open
Volume5
Issue number1
DOIs
Publication statusPublished - Mar 1 2019

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Osteoarthritis
Foot
Exercise
Synovitis
Cartilage
Osteophyte
Joints

Keywords

  • osteoarthritis
  • outcomes research
  • ultrasonography

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

Cite this

Zabotti, A., Filippou, G., Canzoni, M., Adinolfi, A., Picerno, V., Carrara, G., ... Iagnocco, A. (2019). OMERACT agreement and reliability study of ultrasonographic elementary lesions in osteoarthritis of the foot. RMD Open, 5(1), [e000795]. https://doi.org/10.1136/rmdopen-2018-000795

OMERACT agreement and reliability study of ultrasonographic elementary lesions in osteoarthritis of the foot. / Zabotti, Alen; Filippou, Georgios; Canzoni, Marco; Adinolfi, Antonella; Picerno, Valentina; Carrara, Greta; Balint, Peter; Bruyn, George; D'Agostino, Maria Antonietta; Damjanov, Nemanja; Delle Sedie, Andrea; Filippucci, Emilio; Gonzalez Fernandez, Maria Luz; Hammer, Hilde Berner; Karim, Zunaid; Mandl, Peter; Moller, Ingrid; Morales Lozano, Maria Rosario; Naredo, Esperanza; Porta, Francesco; Sakellariou, Garifallia; Terslev, Lene; Scirè, Carlo Alberto; Iagnocco, Annamaria.

In: RMD Open, Vol. 5, No. 1, e000795, 01.03.2019.

Research output: Contribution to journalArticle

Zabotti, A, Filippou, G, Canzoni, M, Adinolfi, A, Picerno, V, Carrara, G, Balint, P, Bruyn, G, D'Agostino, MA, Damjanov, N, Delle Sedie, A, Filippucci, E, Gonzalez Fernandez, ML, Hammer, HB, Karim, Z, Mandl, P, Moller, I, Morales Lozano, MR, Naredo, E, Porta, F, Sakellariou, G, Terslev, L, Scirè, CA & Iagnocco, A 2019, 'OMERACT agreement and reliability study of ultrasonographic elementary lesions in osteoarthritis of the foot', RMD Open, vol. 5, no. 1, e000795. https://doi.org/10.1136/rmdopen-2018-000795
Zabotti, Alen ; Filippou, Georgios ; Canzoni, Marco ; Adinolfi, Antonella ; Picerno, Valentina ; Carrara, Greta ; Balint, Peter ; Bruyn, George ; D'Agostino, Maria Antonietta ; Damjanov, Nemanja ; Delle Sedie, Andrea ; Filippucci, Emilio ; Gonzalez Fernandez, Maria Luz ; Hammer, Hilde Berner ; Karim, Zunaid ; Mandl, Peter ; Moller, Ingrid ; Morales Lozano, Maria Rosario ; Naredo, Esperanza ; Porta, Francesco ; Sakellariou, Garifallia ; Terslev, Lene ; Scirè, Carlo Alberto ; Iagnocco, Annamaria. / OMERACT agreement and reliability study of ultrasonographic elementary lesions in osteoarthritis of the foot. In: RMD Open. 2019 ; Vol. 5, No. 1.
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abstract = "Objective To evaluate the level of agreement on ultrasonographic (US) lesions among highly experienced sonographers as well as the intraobserver and interobserver reliability of inflammatory and structural US lesions in patients with osteoarthritis (OA) of the foot. Methods After a systematic literature review, a Delphi survey was performed to test definitions of US lesions in OA of the foot, including inflammatory lesions (ie, synovial hypertrophy [SH], joint effusion [JE], power Doppler signal [PD]), and structural abnormalities (ie, cartilage damage [CD] and osteophytes). Subsequently, the reliability of US in assessing the aforementioned lesions was tested on static images as well as during a live exercise. Reliability was assessed by kappa analyses and prevalence-adjusted bias-adjusted kappa (PABAK) on a dichotomous and an ordinal scale. Results Intraobserver and interobserver reliability for SH and JE evaluated by binary scoring was good for both components, while the intraobserver reliability for semiquantitative scoring of SH ranged from moderate in the web-based exercise (PABAK 0.49) to good (PABAK 0.8) in the live exercise. Reliability for CD and PD assessments were respectively good and excellent in all exercises (ranged from PABAK 0.61 to 0.79 for CD and 0.88 to 0.95 for PD). The interobserver reliability for the semiquantitative scoring of osteophytes was fair in the live exercise (PABAK 0.36) and moderate in the static exercise (PABAK 0.60). Conclusions Consensual US definitions were found to be reliable for assessing inflammatory lesions in OA of the foot, while the use of US to assess structural damage requires further studies.",
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T1 - OMERACT agreement and reliability study of ultrasonographic elementary lesions in osteoarthritis of the foot

AU - Zabotti, Alen

AU - Filippou, Georgios

AU - Canzoni, Marco

AU - Adinolfi, Antonella

AU - Picerno, Valentina

AU - Carrara, Greta

AU - Balint, Peter

AU - Bruyn, George

AU - D'Agostino, Maria Antonietta

AU - Damjanov, Nemanja

AU - Delle Sedie, Andrea

AU - Filippucci, Emilio

AU - Gonzalez Fernandez, Maria Luz

AU - Hammer, Hilde Berner

AU - Karim, Zunaid

AU - Mandl, Peter

AU - Moller, Ingrid

AU - Morales Lozano, Maria Rosario

AU - Naredo, Esperanza

AU - Porta, Francesco

AU - Sakellariou, Garifallia

AU - Terslev, Lene

AU - Scirè, Carlo Alberto

AU - Iagnocco, Annamaria

PY - 2019/3/1

Y1 - 2019/3/1

N2 - Objective To evaluate the level of agreement on ultrasonographic (US) lesions among highly experienced sonographers as well as the intraobserver and interobserver reliability of inflammatory and structural US lesions in patients with osteoarthritis (OA) of the foot. Methods After a systematic literature review, a Delphi survey was performed to test definitions of US lesions in OA of the foot, including inflammatory lesions (ie, synovial hypertrophy [SH], joint effusion [JE], power Doppler signal [PD]), and structural abnormalities (ie, cartilage damage [CD] and osteophytes). Subsequently, the reliability of US in assessing the aforementioned lesions was tested on static images as well as during a live exercise. Reliability was assessed by kappa analyses and prevalence-adjusted bias-adjusted kappa (PABAK) on a dichotomous and an ordinal scale. Results Intraobserver and interobserver reliability for SH and JE evaluated by binary scoring was good for both components, while the intraobserver reliability for semiquantitative scoring of SH ranged from moderate in the web-based exercise (PABAK 0.49) to good (PABAK 0.8) in the live exercise. Reliability for CD and PD assessments were respectively good and excellent in all exercises (ranged from PABAK 0.61 to 0.79 for CD and 0.88 to 0.95 for PD). The interobserver reliability for the semiquantitative scoring of osteophytes was fair in the live exercise (PABAK 0.36) and moderate in the static exercise (PABAK 0.60). Conclusions Consensual US definitions were found to be reliable for assessing inflammatory lesions in OA of the foot, while the use of US to assess structural damage requires further studies.

AB - Objective To evaluate the level of agreement on ultrasonographic (US) lesions among highly experienced sonographers as well as the intraobserver and interobserver reliability of inflammatory and structural US lesions in patients with osteoarthritis (OA) of the foot. Methods After a systematic literature review, a Delphi survey was performed to test definitions of US lesions in OA of the foot, including inflammatory lesions (ie, synovial hypertrophy [SH], joint effusion [JE], power Doppler signal [PD]), and structural abnormalities (ie, cartilage damage [CD] and osteophytes). Subsequently, the reliability of US in assessing the aforementioned lesions was tested on static images as well as during a live exercise. Reliability was assessed by kappa analyses and prevalence-adjusted bias-adjusted kappa (PABAK) on a dichotomous and an ordinal scale. Results Intraobserver and interobserver reliability for SH and JE evaluated by binary scoring was good for both components, while the intraobserver reliability for semiquantitative scoring of SH ranged from moderate in the web-based exercise (PABAK 0.49) to good (PABAK 0.8) in the live exercise. Reliability for CD and PD assessments were respectively good and excellent in all exercises (ranged from PABAK 0.61 to 0.79 for CD and 0.88 to 0.95 for PD). The interobserver reliability for the semiquantitative scoring of osteophytes was fair in the live exercise (PABAK 0.36) and moderate in the static exercise (PABAK 0.60). Conclusions Consensual US definitions were found to be reliable for assessing inflammatory lesions in OA of the foot, while the use of US to assess structural damage requires further studies.

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KW - outcomes research

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