Abstract
Omission of axillary dissection in women with breast cancer and one or two positive sentinel-node biopsy is a major advancement in the management of this disease. Supported by a sound rationale and confirmed by prospective, randomized trials, omission of axillary dissection is now recommended in women who have undergone breast conserving surgery and who are candidate to adjuvant radiotherapy. Because breast cancer is best managed in the context of a multidisciplinary team, this surgical shift in the paradigm is expected to have implications that extend also to the other specialties involved in the team.In fact, the full evaluation of the axillary tumor burden has been historically considered an essential part of tumor staging and the absolute number of involved node critical information to tailor post-surgical treatments. Lack of this information in a patient with axillary involvement documented by a positive sentinel lymph-node biopsy may represent a challenge when deciding on further, post-surgical treatments. This review will address the critical aspects and the potential implications of omission of axillary dissection in the context of the multidisciplinary breast team.
| Original language | English |
|---|---|
| Pages (from-to) | 1-7 |
| Number of pages | 7 |
| Journal | Cancer Treatment Reviews |
| Volume | 48 |
| DOIs | |
| Publication status | Published - Jul 1 2016 |
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Keywords
- Breast cancer
- Chemotherapy
- Multidisciplinary breast team
- Prognosis
- Radiotherapy
- Sentinel lymph-node biopsy
ASJC Scopus subject areas
- Oncology
- Radiology Nuclear Medicine and imaging
Cite this
Omission of axillary dissection after a positive sentinel lymph-node : Implications in the multidisciplinary treatment of operable breast cancer. / Ponzone, Riccardo; Ruatta, Fiorella; Gatti, Marco; Castellano, Isabella; Geuna, Elena; Amato, Giulia; Kubatzki, Franziska; Sgandurra, Paola; Sapino, Anna; Montemurro, Filippo.
In: Cancer Treatment Reviews, Vol. 48, 01.07.2016, p. 1-7.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Omission of axillary dissection after a positive sentinel lymph-node
T2 - Implications in the multidisciplinary treatment of operable breast cancer
AU - Ponzone, Riccardo
AU - Ruatta, Fiorella
AU - Gatti, Marco
AU - Castellano, Isabella
AU - Geuna, Elena
AU - Amato, Giulia
AU - Kubatzki, Franziska
AU - Sgandurra, Paola
AU - Sapino, Anna
AU - Montemurro, Filippo
PY - 2016/7/1
Y1 - 2016/7/1
N2 - Omission of axillary dissection in women with breast cancer and one or two positive sentinel-node biopsy is a major advancement in the management of this disease. Supported by a sound rationale and confirmed by prospective, randomized trials, omission of axillary dissection is now recommended in women who have undergone breast conserving surgery and who are candidate to adjuvant radiotherapy. Because breast cancer is best managed in the context of a multidisciplinary team, this surgical shift in the paradigm is expected to have implications that extend also to the other specialties involved in the team.In fact, the full evaluation of the axillary tumor burden has been historically considered an essential part of tumor staging and the absolute number of involved node critical information to tailor post-surgical treatments. Lack of this information in a patient with axillary involvement documented by a positive sentinel lymph-node biopsy may represent a challenge when deciding on further, post-surgical treatments. This review will address the critical aspects and the potential implications of omission of axillary dissection in the context of the multidisciplinary breast team.
AB - Omission of axillary dissection in women with breast cancer and one or two positive sentinel-node biopsy is a major advancement in the management of this disease. Supported by a sound rationale and confirmed by prospective, randomized trials, omission of axillary dissection is now recommended in women who have undergone breast conserving surgery and who are candidate to adjuvant radiotherapy. Because breast cancer is best managed in the context of a multidisciplinary team, this surgical shift in the paradigm is expected to have implications that extend also to the other specialties involved in the team.In fact, the full evaluation of the axillary tumor burden has been historically considered an essential part of tumor staging and the absolute number of involved node critical information to tailor post-surgical treatments. Lack of this information in a patient with axillary involvement documented by a positive sentinel lymph-node biopsy may represent a challenge when deciding on further, post-surgical treatments. This review will address the critical aspects and the potential implications of omission of axillary dissection in the context of the multidisciplinary breast team.
KW - Breast cancer
KW - Chemotherapy
KW - Multidisciplinary breast team
KW - Prognosis
KW - Radiotherapy
KW - Sentinel lymph-node biopsy
UR - http://www.scopus.com/inward/record.url?scp=84973641948&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84973641948&partnerID=8YFLogxK
U2 - 10.1016/j.ctrv.2016.05.005
DO - 10.1016/j.ctrv.2016.05.005
M3 - Review article
AN - SCOPUS:84973641948
VL - 48
SP - 1
EP - 7
JO - Cancer Treatment Reviews
JF - Cancer Treatment Reviews
SN - 0305-7372
ER -