On the delineation of the gross tumor volume and clinical target volume for head and neck squamous cell carcinomas

G. Sanguineti, F. Foppiano, M. Marcenaro, F. Roncallo, R. Corvò, F. Ameli, V. Vitale

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Gross tumor volume (GTV) and clinical target volume (CTV) delineation on planning computed tomography (pICT) for head and neck squamous cell carcinomas can be troublesome. We highlight the factors which can be crucial for the radiation oncologist in delineating GTV and CTV on pICT and provide some pratical solutions. Regarding GTV, uncertainties are correlated with transfer of information collected by physical examination and diagnostic radiology to pICT. Moreover, reproducibility of delineation can also be highly variable, particularly when diagnostic imaging quality and pICT quality are poor. Once the prescription has been made, clinical target volume identification on pICT is rarely straightforward. Whereas there are some data about the location of major lymph node stations of the neck, there are no reported guidelines on how to draw subclinical extention of primary head and neck tumors on pICT. Such volumes can be derived from those currently included in simulator films or from those addressed by the surgeon. Some examples are provided. A particular situation is represented by the adjuvant setting, when the primary tumor is removed (by surgery) or reduced (by chemotherapy). In conclusion, this paper shows some major problems associated with identification of GTV and CTV on pICT. Apart from selected cases, the use of pICT for target volume delineation (and thus for field shaping) for head and neck squamous cell carcinoma is still to be considered investigational.

Original languageEnglish
Pages (from-to)152-161
Number of pages10
JournalTumori
Volume87
Issue number3
Publication statusPublished - 2001

Fingerprint

Tumor Burden
Tomography
Neck
Cone-Beam Computed Tomography
Diagnostic Imaging
Motion Pictures
Carcinoma, squamous cell of head and neck
Radiology
Physical Examination
Uncertainty
Prescriptions
Neoplasms
Lymph Nodes
Head
Guidelines
Drug Therapy

Keywords

  • Clinical target volume
  • Gross tumor volume
  • Head and neck carcinoma
  • Radiotherapy

ASJC Scopus subject areas

  • Cancer Research

Cite this

On the delineation of the gross tumor volume and clinical target volume for head and neck squamous cell carcinomas. / Sanguineti, G.; Foppiano, F.; Marcenaro, M.; Roncallo, F.; Corvò, R.; Ameli, F.; Vitale, V.

In: Tumori, Vol. 87, No. 3, 2001, p. 152-161.

Research output: Contribution to journalArticle

Sanguineti, G, Foppiano, F, Marcenaro, M, Roncallo, F, Corvò, R, Ameli, F & Vitale, V 2001, 'On the delineation of the gross tumor volume and clinical target volume for head and neck squamous cell carcinomas', Tumori, vol. 87, no. 3, pp. 152-161.
Sanguineti, G. ; Foppiano, F. ; Marcenaro, M. ; Roncallo, F. ; Corvò, R. ; Ameli, F. ; Vitale, V. / On the delineation of the gross tumor volume and clinical target volume for head and neck squamous cell carcinomas. In: Tumori. 2001 ; Vol. 87, No. 3. pp. 152-161.
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