On the mode of action of Clostridiumdifficile toxin A: an invitro study

C. Fiorentini, G. Donelli, P. Nicotera, P. Mastrantonio, M. Thelestam

Research output: Contribution to journalArticlepeer-review

Abstract

C. difficile toxin A causes the rounding up and the formation of surface blebs in normal rat intestinal crypt cells (IEC-6). These phenomena, together with the inhibition of DNA synthesis and the cell lysis, could be the mechanisms leading the toxin-treated cells to death.

Original languageEnglish
Pages (from-to)84-85
Number of pages2
JournalCytotechnology
Volume5
Issue number1 Supplement
DOIs
Publication statusPublished - Feb 1991

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Cell Biology
  • Biotechnology

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