Abstract
A 49,XXXXX fetus was detected in amniotic fluid cell cultures from a 39-year-old mother. On ultrasonography, growth retardation and bilateral radioulnar synostosis were found. Additional clinical manifestations were mild facial anomalies and hypoplastic ovaries depleted of oocytes. Molecular analysis showed that this aneuploidy arose by successive maternal non-disjunction.
Original language | English |
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Pages (from-to) | 763-766 |
Number of pages | 4 |
Journal | Prenatal Diagnosis |
Volume | 13 |
Issue number | 8 |
Publication status | Published - 1993 |
Keywords
- 49,XXXXX
- Molecular analysis
- Non-disjunction
- Ovary atrophy
- Pentasomy X
- Prenatal diagnosis
ASJC Scopus subject areas
- Genetics(clinical)
- Obstetrics and Gynaecology