TY - JOUR
T1 - On the relation of rat's external cuneate activity to global parameters of forelimb posture
AU - Giaquinta, Genoveffa
AU - Casabona, Antonino
AU - Valle, Maria Stella
AU - Bosco, Gianfranco
AU - Perciavalle, Vincenzo
PY - 1999/9/29
Y1 - 1999/9/29
N2 - Using anesthetized adult rats, we studied the relationships between the activity of cells belonging to the external cuneate nucleus (ECN) and passive forelimb positions. In essence, we sought to distinguish between a representation of limb position based on local limb parameters (individual joint angles, for example) or a representation based on more global parameters such as the length and the orientation of the limb axis. Using multivariate regression analyses we found that most neurons showed strong linear relationships with the length and the orientation of the limb axis. Relationships to individual joint angles were, instead, rather weak and in most cases not significant. This result implies an extensive integration of sensory information at the level of second order sensory neurons.
AB - Using anesthetized adult rats, we studied the relationships between the activity of cells belonging to the external cuneate nucleus (ECN) and passive forelimb positions. In essence, we sought to distinguish between a representation of limb position based on local limb parameters (individual joint angles, for example) or a representation based on more global parameters such as the length and the orientation of the limb axis. Using multivariate regression analyses we found that most neurons showed strong linear relationships with the length and the orientation of the limb axis. Relationships to individual joint angles were, instead, rather weak and in most cases not significant. This result implies an extensive integration of sensory information at the level of second order sensory neurons.
KW - Cerebellum
KW - Forelimb position
KW - Proprioception
KW - Sensorimotor integration
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M3 - Article
C2 - 10549826
AN - SCOPUS:0033615245
VL - 10
SP - 3075
EP - 3080
JO - NeuroReport
JF - NeuroReport
SN - 0959-4965
IS - 14
ER -