On the relation of rat's external cuneate activity to global parameters of forelimb posture

Genoveffa Giaquinta, Antonino Casabona, Maria Stella Valle, Gianfranco Bosco, Vincenzo Perciavalle

Research output: Contribution to journalArticle

Abstract

Using anesthetized adult rats, we studied the relationships between the activity of cells belonging to the external cuneate nucleus (ECN) and passive forelimb positions. In essence, we sought to distinguish between a representation of limb position based on local limb parameters (individual joint angles, for example) or a representation based on more global parameters such as the length and the orientation of the limb axis. Using multivariate regression analyses we found that most neurons showed strong linear relationships with the length and the orientation of the limb axis. Relationships to individual joint angles were, instead, rather weak and in most cases not significant. This result implies an extensive integration of sensory information at the level of second order sensory neurons.

Original languageEnglish
Pages (from-to)3075-3080
Number of pages6
JournalNeuroReport
Volume10
Issue number14
Publication statusPublished - Sep 29 1999

Keywords

  • Cerebellum
  • Forelimb position
  • Proprioception
  • Sensorimotor integration

ASJC Scopus subject areas

  • Neuroscience(all)

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  • Cite this

    Giaquinta, G., Casabona, A., Valle, M. S., Bosco, G., & Perciavalle, V. (1999). On the relation of rat's external cuneate activity to global parameters of forelimb posture. NeuroReport, 10(14), 3075-3080.