Oncogene expression in follicular neoplasms of the thyroid

Louis Joseph Auguste, Shahla Masood, Alex Westerband, Claudio Belluco, Elsa Valderamma, Joseph Attie

Research output: Contribution to journalArticlepeer-review

Abstract

Oncogene expression has been found to be a potential marker for aggressive biologic behavior in certain tumors. We studied 21 follicular adenomas and 20 follicular carcinomas by immunocytochemistry utilizing specific monoclonal antibodies against HER-2/neu and c-myc oncogenes. Survival data were obtained from our institution's tumor registry. No expression of the HER-2/neu oncogene was found in the specimens studied. Cytoplasmic staining for c-myc was observed in 3 of 21 adenomas (14%) and 9 of 20 (45%) carcinomas (p

Original languageEnglish
Pages (from-to)592-593
Number of pages2
JournalAmerican Journal of Surgery
Volume164
Issue number6
DOIs
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Surgery

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