One Clever Macrophage Checkpoint

Research output: Contribution to journalArticle

Abstract

Macrophages are a key component of the tumor microenvironment (TME). Blocking Clever-1, a molecule expressed in M2-like macrophages, unleashed macrophage and T-cell-mediated antitumor immunity. Myeloid checkpoints including Clever-1 hold promise as alternative or complementary immunotherapy strategies.See related article by Viitala et al., p. 3289.

Original languageEnglish
Pages (from-to)3202-3204
Number of pages3
JournalClinical Cancer Research
Volume25
Issue number11
DOIs
Publication statusPublished - Jun 1 2019

Keywords

  • Immunologic Factors
  • Immunotherapy
  • Macrophages/immunology
  • Tumor Microenvironment/immunology

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