TY - JOUR
T1 - One-year follow-up after single procedure cryoballoon ablation
T2 - A comparison between the first and second generation balloon
AU - Giovanni, Giacomo Di
AU - Wauters, Kristel
AU - Chierchia, Gian Battista
AU - Sieira, Juan
AU - Levinstein, Moises
AU - Conte, Giulio
AU - De Asmundis, Carlo
AU - Baltogiannis, Giannis
AU - Saitoh, Yukio
AU - Ciconte, Giuseppe
AU - Julia, Justo
AU - Mugnai, Giacomo
AU - Irfan, Ghazala
AU - Brugada, Pedro
PY - 2014
Y1 - 2014
N2 - A Comparison Between the First and Second Generation Balloon Background With respect to the first generation Cryoballoon (CB), the second generation (Cryoballoon Advance [CB-A], Medtronic, Minneapolis, MN, USA) was designed with technical modifications resulting in a larger and more uniform zone of freezing on the balloon's surface aiming at procedural outcome improvement in the setting of atrial fibrillation (AF) ablation. However, a comparison between both technologies on a midterm follow-up is missing in today's literature. Methods A total of 100 patients (the last 50 patients with the first generation CB and the first 50 patients with the second generation CB-A upon its inception in our center) having undergone a single CB ablation for paroxysmal AF (PAF) and having completed a 12-month follow-up, were consecutively included in our study. Freedom from AF off-antiarrhythmic drugs (AADs) after a single procedure was 78% (39/50) in CB-A and 58% (29/50) in the CB group (P = 0.03) during the whole follow-up duration. Considering a blanking period of 3 months, freedom from AF off-AAD was achieved in 84% (42/50) in CB-A, while 66% (33/50) were free from recurrence in the CB group (P = 0.038). Right phrenic nerve palsy (PNP) occurred in 8 patients (16%) in CB-A group and in 4 patients (8%) in the CB group. Conclusion Freedom from AF on 12 months follow-up was significantly higher in the CB-A group with respect to the first generation device. The most frequent complication observed was PNP.
AB - A Comparison Between the First and Second Generation Balloon Background With respect to the first generation Cryoballoon (CB), the second generation (Cryoballoon Advance [CB-A], Medtronic, Minneapolis, MN, USA) was designed with technical modifications resulting in a larger and more uniform zone of freezing on the balloon's surface aiming at procedural outcome improvement in the setting of atrial fibrillation (AF) ablation. However, a comparison between both technologies on a midterm follow-up is missing in today's literature. Methods A total of 100 patients (the last 50 patients with the first generation CB and the first 50 patients with the second generation CB-A upon its inception in our center) having undergone a single CB ablation for paroxysmal AF (PAF) and having completed a 12-month follow-up, were consecutively included in our study. Freedom from AF off-antiarrhythmic drugs (AADs) after a single procedure was 78% (39/50) in CB-A and 58% (29/50) in the CB group (P = 0.03) during the whole follow-up duration. Considering a blanking period of 3 months, freedom from AF off-AAD was achieved in 84% (42/50) in CB-A, while 66% (33/50) were free from recurrence in the CB group (P = 0.038). Right phrenic nerve palsy (PNP) occurred in 8 patients (16%) in CB-A group and in 4 patients (8%) in the CB group. Conclusion Freedom from AF on 12 months follow-up was significantly higher in the CB-A group with respect to the first generation device. The most frequent complication observed was PNP.
KW - atrial fibrillation
KW - catheter ablation
KW - cryoballoon
KW - phrenic nerve
KW - pulmonary vein isolation
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U2 - 10.1111/jce.12409
DO - 10.1111/jce.12409
M3 - Article
C2 - 24641307
AN - SCOPUS:84905923920
VL - 25
SP - 834
EP - 839
JO - Journal of Cardiovascular Electrophysiology
JF - Journal of Cardiovascular Electrophysiology
SN - 1045-3873
IS - 8
ER -