Abstract
Objectives To determine whether type 2 diabetes mellitus and hyperglycemia on admission should be considered independent predictors of mortality in elderly adults with acute coronary syndrome (ACS). Design Prospective cohort study. Setting Twenty-three hospitals in Italy. Participants Individuals aged 75 and older with non-ST-elevation ACS (NSTEACS) (mean age 82, 47% female) (N = 645). Measurements Diabetic status and blood glucose levels were assessed on admission. Hyperglycemia was defined as glucose greater than 140 mg/dL. Multivariable Cox proportional hazard regression was used to assess the potential confounding effect of major covariates on the association between diabetic status, admission glucose, and 1-year mortality. Results A history of diabetes mellitus was found in 231 participants (35.8%), whereas 257 (39.8%) had hyperglycemia. Hyperglycemia was found in 171 participants with diabetes mellitus (70%) and 86 (21%) without diabetes mellitus. Participants with diabetes mellitus were significantly (P
| Original language | English |
|---|---|
| Pages (from-to) | 1297-1303 |
| Number of pages | 7 |
| Journal | Journal of the American Geriatrics Society |
| Volume | 62 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 2014 |
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Keywords
- acute coronary syndrome
- diabetes mellitus
- elderly
- hyperglycemia
- mortality
ASJC Scopus subject areas
- Geriatrics and Gerontology
Cite this
One-year mortality in elderly adults with non-st-elevation acute coronary syndrome : Effect of diabetic status and admission hyperglycemia. / Savonitto, Stefano; Morici, Nuccia; Cavallini, Claudio; Antonicelli, Roberto; Petronio, Anna Sonia; Murena, Ernesto; Olivari, Zoran; Steffenino, Giuseppe; Bonechi, Francesco; Mafrici, Antonio; Toso, Anna; Piscione, Federico; Bolognese, Leonardo; De Servi, Stefano.
In: Journal of the American Geriatrics Society, Vol. 62, No. 7, 2014, p. 1297-1303.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - One-year mortality in elderly adults with non-st-elevation acute coronary syndrome
T2 - Effect of diabetic status and admission hyperglycemia
AU - Savonitto, Stefano
AU - Morici, Nuccia
AU - Cavallini, Claudio
AU - Antonicelli, Roberto
AU - Petronio, Anna Sonia
AU - Murena, Ernesto
AU - Olivari, Zoran
AU - Steffenino, Giuseppe
AU - Bonechi, Francesco
AU - Mafrici, Antonio
AU - Toso, Anna
AU - Piscione, Federico
AU - Bolognese, Leonardo
AU - De Servi, Stefano
PY - 2014
Y1 - 2014
N2 - Objectives To determine whether type 2 diabetes mellitus and hyperglycemia on admission should be considered independent predictors of mortality in elderly adults with acute coronary syndrome (ACS). Design Prospective cohort study. Setting Twenty-three hospitals in Italy. Participants Individuals aged 75 and older with non-ST-elevation ACS (NSTEACS) (mean age 82, 47% female) (N = 645). Measurements Diabetic status and blood glucose levels were assessed on admission. Hyperglycemia was defined as glucose greater than 140 mg/dL. Multivariable Cox proportional hazard regression was used to assess the potential confounding effect of major covariates on the association between diabetic status, admission glucose, and 1-year mortality. Results A history of diabetes mellitus was found in 231 participants (35.8%), whereas 257 (39.8%) had hyperglycemia. Hyperglycemia was found in 171 participants with diabetes mellitus (70%) and 86 (21%) without diabetes mellitus. Participants with diabetes mellitus were significantly (P
AB - Objectives To determine whether type 2 diabetes mellitus and hyperglycemia on admission should be considered independent predictors of mortality in elderly adults with acute coronary syndrome (ACS). Design Prospective cohort study. Setting Twenty-three hospitals in Italy. Participants Individuals aged 75 and older with non-ST-elevation ACS (NSTEACS) (mean age 82, 47% female) (N = 645). Measurements Diabetic status and blood glucose levels were assessed on admission. Hyperglycemia was defined as glucose greater than 140 mg/dL. Multivariable Cox proportional hazard regression was used to assess the potential confounding effect of major covariates on the association between diabetic status, admission glucose, and 1-year mortality. Results A history of diabetes mellitus was found in 231 participants (35.8%), whereas 257 (39.8%) had hyperglycemia. Hyperglycemia was found in 171 participants with diabetes mellitus (70%) and 86 (21%) without diabetes mellitus. Participants with diabetes mellitus were significantly (P
KW - acute coronary syndrome
KW - diabetes mellitus
KW - elderly
KW - hyperglycemia
KW - mortality
UR - http://www.scopus.com/inward/record.url?scp=84904512415&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84904512415&partnerID=8YFLogxK
U2 - 10.1111/jgs.12900
DO - 10.1111/jgs.12900
M3 - Article
C2 - 24917216
AN - SCOPUS:84904512415
VL - 62
SP - 1297
EP - 1303
JO - Journal of the American Geriatrics Society
JF - Journal of the American Geriatrics Society
SN - 0002-8614
IS - 7
ER -