One-year prognosis of primary ventricular fibrillation complicating acute myocardial infarction

Alberto Volpi, Augusto Cavalli, Maria Grazia Franzosi, Aldo Maggioni, Francesco Mauri, Eugenio Santoro, Gianni Tognoni, GISSI Investigators The GISSI Investigators

Research output: Contribution to journalArticlepeer-review


The 1-year prognosis of 293 patients discharged alive from the hospital after acute myocardial infarction (AMI), who experienced primary ventricular fibrillation (VF) in the acute phase, was compared with that of a reference group of 6,337 patients identified from the same population included in the Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto miocardico (GISSI) trial. There was no difference in the 6- and 12-month mortality between the patients with primary VF and the reference group (3.7 vs 2.7% and 4.1 vs 4.2%, respectively). Survival of the 2 groups was also similar when patients were stratified according to infarct site (anterior and posterior), and whether or not they received treatment with streptokinase during AMI. Thus, long-term mortality of patients discharged alive after AMI complicated by primary VF is low and is not influenced by previous fibrinolytic therapy or by infarct site. The excess mortality of patients with primary VF is confined to the hospital phase, after which survivors represent a low-risk subgroup.

Original languageEnglish
Pages (from-to)1174-1178
Number of pages5
JournalThe American Journal of Cardiology
Issue number17
Publication statusPublished - May 15 1989

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'One-year prognosis of primary ventricular fibrillation complicating acute myocardial infarction'. Together they form a unique fingerprint.

Cite this