One year treatment with lisuride delivery pump in Parkinson's disease

Stefano Ruggieri; Fabrizio Stocchi; Angelico Carta; Maura Bragoni; Claudio Agostini; Luca Barbato; Alessandro Agnoli

doi:10.1016/0278-5846(89)90015-8

One year treatment with lisuride delivery pump in Parkinson's disease

Stefano Ruggieri, Fabrizio Stocchi, Angelico Carta, Maura Bragoni, Claudio Agostini, Luca Barbato, Alessandro Agnoli

Research output: Contribution to journal › Article › peer-review

Abstract

1. A group of 14 fluctuating Parkinsonian patients underwent the subcutaneous Lisuride treatment, administered by an insulin delivery pump. Clinical response has been studied during a one year period. 2. Some patients (8 out of 14) were in combined therapy, assuming a relative small amount of oral L-Dopa togheter with subcutaneous Lisuride. 3. Lisuride confirmed, also by the subcutaneous route, its antiparkinsonian properties, without any loss of therapeutical efficacy during the 12 month period considered. 4. 7 patients dropped-out from the study, due to psychiatric or systemic side-effects and to "technical" management of the pump. 5. The only 2 patients assuming a 24 hour regimen of Lisuride infusion were among the withdrawn subjects. They were also the only to complain severe psychiatric disturbances.

Original language	English
Pages (from-to)	173-183
Number of pages	11
Journal	Progress in Neuro-Psychopharmacology and Biological Psychiatry
Volume	13
Issue number	1-2
DOIs	https://doi.org/10.1016/0278-5846(89)90015-8
Publication status	Published - 1989

Keywords

fluctuations
Lisuride
pump
subcutaneous

ASJC Scopus subject areas

Biological Psychiatry
Pharmacology

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10.1016/0278-5846(89)90015-8

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AU - Ruggieri, Stefano

AU - Stocchi, Fabrizio

AU - Carta, Angelico

AU - Bragoni, Maura

AU - Agostini, Claudio

AU - Barbato, Luca

AU - Agnoli, Alessandro

PY - 1989

Y1 - 1989

N2 - 1. A group of 14 fluctuating Parkinsonian patients underwent the subcutaneous Lisuride treatment, administered by an insulin delivery pump. Clinical response has been studied during a one year period. 2. Some patients (8 out of 14) were in combined therapy, assuming a relative small amount of oral L-Dopa togheter with subcutaneous Lisuride. 3. Lisuride confirmed, also by the subcutaneous route, its antiparkinsonian properties, without any loss of therapeutical efficacy during the 12 month period considered. 4. 7 patients dropped-out from the study, due to psychiatric or systemic side-effects and to "technical" management of the pump. 5. The only 2 patients assuming a 24 hour regimen of Lisuride infusion were among the withdrawn subjects. They were also the only to complain severe psychiatric disturbances.

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KW - fluctuations

KW - Lisuride

KW - pump

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ER -

One year treatment with lisuride delivery pump in Parkinson's disease

Abstract

Keywords

ASJC Scopus subject areas

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