Onycholemmal carcinoma

Elvio Alessi, Antonella Coggi, Raffaele Gianotti, Antonina Parafioriti, Emilio Berti

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

We report on a slowly growing malignant tumor of the nail bed epithelium in a 69-year-old male. On light microscopic examination, the tumor was composed of: (1) some small cysts filled with eosinophilic, amorphous keratin and lined by an atypical squamous epithelium devoid of a granular layer and (2) solid nests and strands of atypical keratinocytes filling the dermis and penetrating the phalangeal bone. Because the nail bed epithelium is comparable to the outer root sheath, or trichilemma of the hair follicle, and since the reported tumor showed some analogies with trichilemmal carcinoma, we suggest that this entity be designated 'onycholemmal carcinoma'. Disarticulation of the involved phalanx was performed and neither local recurrence nor distant metastasis was observed during 4 years of follow up.

Original languageEnglish
Pages (from-to)397-402
Number of pages6
JournalAmerican Journal of Dermatopathology
Volume26
Issue number5
DOIs
Publication statusPublished - Oct 2004

Fingerprint

Epithelium
Nails
Carcinoma
Disarticulation
Neoplasms
Hair Follicle
Dermis
Keratins
Keratinocytes
Cysts
Neoplasm Metastasis
Light
Bone and Bones
Recurrence

Keywords

  • Malignant proliferating onycholemmal cyst
  • Nail apparatus
  • Nail bed
  • Nail bed epithelium
  • Onycholemmal carcinoma
  • Squamous cell carcinoma
  • Trichilemmal carcinoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dermatology

Cite this

Onycholemmal carcinoma. / Alessi, Elvio; Coggi, Antonella; Gianotti, Raffaele; Parafioriti, Antonina; Berti, Emilio.

In: American Journal of Dermatopathology, Vol. 26, No. 5, 10.2004, p. 397-402.

Research output: Contribution to journalArticle

Alessi, Elvio ; Coggi, Antonella ; Gianotti, Raffaele ; Parafioriti, Antonina ; Berti, Emilio. / Onycholemmal carcinoma. In: American Journal of Dermatopathology. 2004 ; Vol. 26, No. 5. pp. 397-402.
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