From 1960 to 1972, 639 patients underwent bilateral oophorectomy for carcinoma of the breast. The overall regression rate was 29.5%; regressions lasted on an average of 16 mth, and 19% of the patients who responded to surgery survived 5 yr or longer. The best results were achieved when the patients were premenopausal and over 35 yr of age or not more than 1 yr menopausal, if the free interval was longer than 2 yr or if the patient had primary advanced carcinoma and when the lesions were localized to the soft tissues, bones, lung and pleura. Attempts to demonstrate the hormone dependence of the tumor by correlating the response rate to preoperative urinary steroid determination or by cytologic examination of the vaginal smear were inconclusive.
|Number of pages||2|
|Journal||Surgery Gynecology and Obstetrics|
|Publication status||Published - 1975|
ASJC Scopus subject areas
- Obstetrics and Gynaecology