Open loop linear parametric modeling of the QT variability

Alberto Porta; Eleonora Tobaldini; Valentina Magagnin; Tito Bassani; Tomaso Gnecchi-Ruscone; Nicola Montano

doi:10.1109/IEMBS.2009.5333541

Open loop linear parametric modeling of the QT variability

Alberto Porta, Eleonora Tobaldini, Valentina Magagnin, Tito Bassani, Tomaso Gnecchi-Ruscone, Nicola Montano

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Open loop linear parametric modeling approach was applied to describe the variability of the ventricular depolarization and repolarization duration (i.e. the QT interval from the ECG). Several model structures were compared. The model maximizing the goodness of fit describes the QT interval as a linear combination of its own past values plus two exogenous influences (i.e. heart period interval and respiration) and a colored noise. When this model was applied to a protocol imposing a progressive increase of the sympathetic activity and modulation (i.e. the graded head-up tilt), the goodness of fit gradually decreased, thus suggesting a progressive uncoupling between QT duration and heart period that cannot be the result of influences unrelated to heart period changes.

Original language	English
Title of host publication	Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
Pages	6453-6456
Number of pages	4
DOIs	https://doi.org/10.1109/IEMBS.2009.5333541
Publication status	Published - 2009
Event	31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States Duration: Sep 2 2009 → Sep 6 2009

Other

Other	31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
Country	United States
City	Minneapolis, MN
Period	9/2/09 → 9/6/09

ASJC Scopus subject areas

Cell Biology
Developmental Biology
Biomedical Engineering
Medicine(all)

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Porta, A., Tobaldini, E., Magagnin, V., Bassani, T., Gnecchi-Ruscone, T., & Montano, N. (2009). Open loop linear parametric modeling of the QT variability. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 (pp. 6453-6456). [5333541] https://doi.org/10.1109/IEMBS.2009.5333541

Open loop linear parametric modeling of the QT variability. / Porta, Alberto ; Tobaldini, Eleonora; Magagnin, Valentina; Bassani, Tito; Gnecchi-Ruscone, Tomaso; Montano, Nicola.

Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. 2009. p. 6453-6456 5333541.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Porta, A , Tobaldini, E, Magagnin, V, Bassani, T, Gnecchi-Ruscone, T & Montano, N 2009, Open loop linear parametric modeling of the QT variability. in Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009., 5333541, pp. 6453-6456, 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, Minneapolis, MN, United States, 9/2/09. https://doi.org/10.1109/IEMBS.2009.5333541

Porta A , Tobaldini E, Magagnin V, Bassani T, Gnecchi-Ruscone T, Montano N. Open loop linear parametric modeling of the QT variability. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. 2009. p. 6453-6456. 5333541 https://doi.org/10.1109/IEMBS.2009.5333541

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