Ophthalmoplegic migraine: From questions to answers

Paolo Ambrosetto, Francesca Nicolini, Matteo Zoli, Luigi Cirillo, Paola Feraco, Antonella Bacci

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Introduction: The International Classification of Headache Disorders classifies ophthalmoplegic migraine (OM) under "cranial neuralgias and central causes of facial pain." OM is diagnosed when all the following criteria are satisfied: A. At least two attacks fulfilling criterion B. B. Migraine-like headache accompanied or followed within four days of its onset by paresis of one or more of the III, IV and/or VI cranial nerves. C. Parasellar orbital fissure and posterior fossa lesions ruled out by appropriate investigations. In children the syndrome is rare and magnetic resonance (MR) shows strongly enhancing thickened nerve at the root entry zone (REZ). Method: The authors review the literature focusing on pathogenesis theories. Results: The authors suggest that ischemic reversible breakdown of the blood-nerve barrier is the most probable cause of OM and to include MR findings in the hallmarks of the disease. Conclusion: OM is the same disease in adulthood and childhood, even if in adults the MR imaging findings are negative. In the authors' opinion, OM should be classified as migraine.

Original languageEnglish
Pages (from-to)914-919
Number of pages6
JournalCephalalgia
Volume34
Issue number11
DOIs
Publication statusPublished - Oct 12 2014

Fingerprint

Ophthalmoplegic Migraine
Migraine Disorders
Blood-Nerve Barrier
Magnetic Resonance Spectroscopy
Trochlear Nerve
Abducens Nerve
Oculomotor Nerve
Facial Pain
Headache Disorders
Paresis
Magnetic Resonance Imaging

Keywords

  • Cranial nerve palsy
  • Headache
  • Neuroradiology
  • Ophthalmoplegic migraine
  • Pediatric

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Ophthalmoplegic migraine : From questions to answers. / Ambrosetto, Paolo; Nicolini, Francesca; Zoli, Matteo; Cirillo, Luigi; Feraco, Paola; Bacci, Antonella.

In: Cephalalgia, Vol. 34, No. 11, 12.10.2014, p. 914-919.

Research output: Contribution to journalArticle

Ambrosetto, P, Nicolini, F, Zoli, M, Cirillo, L, Feraco, P & Bacci, A 2014, 'Ophthalmoplegic migraine: From questions to answers', Cephalalgia, vol. 34, no. 11, pp. 914-919. https://doi.org/10.1177/0333102414523843
Ambrosetto, Paolo ; Nicolini, Francesca ; Zoli, Matteo ; Cirillo, Luigi ; Feraco, Paola ; Bacci, Antonella. / Ophthalmoplegic migraine : From questions to answers. In: Cephalalgia. 2014 ; Vol. 34, No. 11. pp. 914-919.
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