Opioid antagonism of electroschock-induced seizures

Stefano Puglisi-Allegra; Claudio Castellano; Vilmos Csányl; Antal Dóka; Alberto Oliverio

doi:10.1016/0091-3057(84)90197-7

Opioid antagonism of electroschock-induced seizures

Stefano Puglisi-Allegra, Claudio Castellano, Vilmos Csányl, Antal Dóka, Alberto Oliverio

Fondazione Santa Lucia

Research output: Contribution to journal › Article › peer-review

Abstract

Morphine, β-endorphin and [D-Ala², D-Leu⁵] enkephalin administered intracerebroventricularly exterted a protective on electroconvulsive shock (ECS)-induced seizures in mice. This effect was reversed by intraperitoneal injections of naltrexone. The role of μ and δ receptors in ECS-induced convulsions is discussed.

Original language	English
Pages (from-to)	767-769
Number of pages	3
Journal	Pharmacology, Biochemistry and Behavior
Volume	20
Issue number	5
DOIs	https://doi.org/10.1016/0091-3057(84)90197-7
Publication status	Published - 1984

Keywords

Electroconvulsive shock
Mice
Morphine
Seizures
[D-Ala, D-Leu] enkephalin
β-Endorphin

ASJC Scopus subject areas

Biochemistry
Behavioral Neuroscience
Pharmacology

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10.1016/0091-3057(84)90197-7

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abstract = "Morphine, β-endorphin and [D-Ala2, D-Leu5] enkephalin administered intracerebroventricularly exterted a protective on electroconvulsive shock (ECS)-induced seizures in mice. This effect was reversed by intraperitoneal injections of naltrexone. The role of μ and δ receptors in ECS-induced convulsions is discussed.",

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author = "Stefano Puglisi-Allegra and Claudio Castellano and Vilmos Cs{\'a}nyl and Antal D{\'o}ka and Alberto Oliverio",

year = "1984",

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T1 - Opioid antagonism of electroschock-induced seizures

AU - Puglisi-Allegra, Stefano

AU - Castellano, Claudio

AU - Csányl, Vilmos

AU - Dóka, Antal

AU - Oliverio, Alberto

PY - 1984

Y1 - 1984

N2 - Morphine, β-endorphin and [D-Ala2, D-Leu5] enkephalin administered intracerebroventricularly exterted a protective on electroconvulsive shock (ECS)-induced seizures in mice. This effect was reversed by intraperitoneal injections of naltrexone. The role of μ and δ receptors in ECS-induced convulsions is discussed.

AB - Morphine, β-endorphin and [D-Ala2, D-Leu5] enkephalin administered intracerebroventricularly exterted a protective on electroconvulsive shock (ECS)-induced seizures in mice. This effect was reversed by intraperitoneal injections of naltrexone. The role of μ and δ receptors in ECS-induced convulsions is discussed.

KW - Electroconvulsive shock

KW - Mice

KW - Morphine

KW - Seizures

KW - [D-Ala, D-Leu] enkephalin

KW - β-Endorphin

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JO - Pharmacology Biochemistry and Behavior

JF - Pharmacology Biochemistry and Behavior

SN - 0091-3057

IS - 5

ER -

Opioid antagonism of electroschock-induced seizures

Abstract

Keywords

ASJC Scopus subject areas

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