Optic nerve involvement in acute lymphoblastic leukemia

A. Camera, G. Piccirillo, G. Cennamo, F. Tranfa, N. Rosa, F. Frigeri, V. Martinelli, B. Rotoli

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Leukemic infiltration of the optic nerve is rare. We describe the diagnostic assessment and the outcome in two adult patients suffering from acute lymphoblastic leukemia with T phe-notype. In both cases the leukemic involvement of the eye was observed as an isolated ex-tramedullary relapse followed after several months by hematological relapse. CT and MRI scans were negative, while an A-scan echography of the eye clarified the diagnosis. Early radiotherapy caused recovery of visual acuity in one case. A-scan echography is the most sensitive investigation for the early recognition of ocular localization in acute leukemias.

Original languageEnglish
Pages (from-to)153-155
Number of pages3
JournalLeukemia and Lymphoma
Volume11
Issue number1-2
DOIs
Publication statusPublished - 1993

Fingerprint

Optic Nerve
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Ultrasonography
Leukemic Infiltration
Recurrence
Visual Acuity
Leukemia
Radiotherapy
Magnetic Resonance Imaging
Outcome Assessment (Health Care)

Keywords

  • Acute lymphoblastic leukemia
  • Ocular echography
  • Optic nerve localization

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

Cite this

Camera, A., Piccirillo, G., Cennamo, G., Tranfa, F., Rosa, N., Frigeri, F., ... Rotoli, B. (1993). Optic nerve involvement in acute lymphoblastic leukemia. Leukemia and Lymphoma, 11(1-2), 153-155. https://doi.org/10.3109/10428199309054745

Optic nerve involvement in acute lymphoblastic leukemia. / Camera, A.; Piccirillo, G.; Cennamo, G.; Tranfa, F.; Rosa, N.; Frigeri, F.; Martinelli, V.; Rotoli, B.

In: Leukemia and Lymphoma, Vol. 11, No. 1-2, 1993, p. 153-155.

Research output: Contribution to journalArticle

Camera, A, Piccirillo, G, Cennamo, G, Tranfa, F, Rosa, N, Frigeri, F, Martinelli, V & Rotoli, B 1993, 'Optic nerve involvement in acute lymphoblastic leukemia', Leukemia and Lymphoma, vol. 11, no. 1-2, pp. 153-155. https://doi.org/10.3109/10428199309054745
Camera, A. ; Piccirillo, G. ; Cennamo, G. ; Tranfa, F. ; Rosa, N. ; Frigeri, F. ; Martinelli, V. ; Rotoli, B. / Optic nerve involvement in acute lymphoblastic leukemia. In: Leukemia and Lymphoma. 1993 ; Vol. 11, No. 1-2. pp. 153-155.
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