Abstract
Leukemic infiltration of the optic nerve is rare. We describe the diagnostic assessment and the outcome in two adult patients suffering from acute lymphoblastic leukemia with T phe-notype. In both cases the leukemic involvement of the eye was observed as an isolated ex-tramedullary relapse followed after several months by hematological relapse. CT and MRI scans were negative, while an A-scan echography of the eye clarified the diagnosis. Early radiotherapy caused recovery of visual acuity in one case. A-scan echography is the most sensitive investigation for the early recognition of ocular localization in acute leukemias.
| Original language | English |
|---|---|
| Pages (from-to) | 153-155 |
| Number of pages | 3 |
| Journal | Leukemia and Lymphoma |
| Volume | 11 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - 1993 |
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Keywords
- Acute lymphoblastic leukemia
- Ocular echography
- Optic nerve localization
ASJC Scopus subject areas
- Hematology
- Oncology
- Cancer Research
Cite this
Optic nerve involvement in acute lymphoblastic leukemia. / Camera, A.; Piccirillo, G.; Cennamo, G.; Tranfa, F.; Rosa, N.; Frigeri, F.; Martinelli, V.; Rotoli, B.
In: Leukemia and Lymphoma, Vol. 11, No. 1-2, 1993, p. 153-155.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Optic nerve involvement in acute lymphoblastic leukemia
AU - Camera, A.
AU - Piccirillo, G.
AU - Cennamo, G.
AU - Tranfa, F.
AU - Rosa, N.
AU - Frigeri, F.
AU - Martinelli, V.
AU - Rotoli, B.
PY - 1993
Y1 - 1993
N2 - Leukemic infiltration of the optic nerve is rare. We describe the diagnostic assessment and the outcome in two adult patients suffering from acute lymphoblastic leukemia with T phe-notype. In both cases the leukemic involvement of the eye was observed as an isolated ex-tramedullary relapse followed after several months by hematological relapse. CT and MRI scans were negative, while an A-scan echography of the eye clarified the diagnosis. Early radiotherapy caused recovery of visual acuity in one case. A-scan echography is the most sensitive investigation for the early recognition of ocular localization in acute leukemias.
AB - Leukemic infiltration of the optic nerve is rare. We describe the diagnostic assessment and the outcome in two adult patients suffering from acute lymphoblastic leukemia with T phe-notype. In both cases the leukemic involvement of the eye was observed as an isolated ex-tramedullary relapse followed after several months by hematological relapse. CT and MRI scans were negative, while an A-scan echography of the eye clarified the diagnosis. Early radiotherapy caused recovery of visual acuity in one case. A-scan echography is the most sensitive investigation for the early recognition of ocular localization in acute leukemias.
KW - Acute lymphoblastic leukemia
KW - Ocular echography
KW - Optic nerve localization
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UR - http://www.scopus.com/inward/citedby.url?scp=0027491339&partnerID=8YFLogxK
U2 - 10.3109/10428199309054745
DO - 10.3109/10428199309054745
M3 - Article
VL - 11
SP - 153
EP - 155
JO - Leukemia and Lymphoma
JF - Leukemia and Lymphoma
SN - 1042-8194
IS - 1-2
ER -