Optical Coherence Tomography Angiography in Children with Leber-Coats Disease

Michele Fortunato, Angela Turtoro, Gilda Cennamo

Research output: Contribution to journalArticlepeer-review


Introduction: The aim of this work was to describe the optical coherence tomography (OCT) angiography (OCTA) features in paediatric Leber-Coats disease. Methods: Three children presenting with unilateral, clinically active Leber-Coats disease were evaluated using spectral domain OCT and OCTA. OCT angiograms were analysed and compared with the current literature. Results: All 3 OCT angiograms showed that the vessels had lost most of their collateral branches and presented many loops. The capillaries were rarefied and anomalies in vessel size, vasodilatation, and macroaneurysms were evident. Conclusion: This is the first case series of OCTA performed in children with Leber-Coats disease. OCTA is a non-invasive and non-contact technique, which can be considered of fundamental importance for the diagnosis, clinical management, and follow-up of the disease.

Original languageEnglish
Pages (from-to)185-187
Number of pages3
JournalOphthalmic Research
Issue number3
Publication statusPublished - Sep 1 2017


  • Leber-Coats disease
  • Optical coherence tomography angiography

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


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