Optical mammography: A new technique for visualizing breast lesions in women presenting non palpable BIRADS 4-5 imaging findings: Preliminary results with radiologic-pathologic correlation

Alexandra Athanasiou, Daniel Vanel, Laure Fournier, Corinne Balleyguier

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The purpose of this prospective study is to determine the diagnostic accuracy of near-infrared breast optical absorption imaging in patients with Breast Imaging Reporting and Data System (BIRADS) 4-5 non-palpable lesions scheduled for biopsy, using pathology after core or excisional biopsy as a reference. The patient's breast was positioned onto a panel of red light-emitting diodes (640nm). A soft membrane was inflated to exert a uniform pressure on the breast. Transmitted light was detected using a CCD camera. The entire acquisition sequence took 1 minute. Image processing generated dynamic images displayed in colour scale, to reveal time-dependent changes in the transmitted light intensity caused by the pressure change. Dynamic curves were classified in two categories: consistently decreasing intensity suspicious for malignancy, and sinusoidal increasing intensity considered as benign. Seventy-eight women consulting for non-palpable breast lesions were initially included in the study. An imaging - histology correlation was obtained for seventy-two patients, the remaining six patients were excluded for technical optical scan reasons. We experienced an overall sensitivity of 73% and specificity of 38%, the false negative results being mainly small size (

Original languageEnglish
Pages (from-to)34-40
Number of pages7
JournalCancer Imaging
Volume7
Issue number1
DOIs
Publication statusPublished - 2007

Fingerprint

Mammography
Information Systems
Breast
Light
Biopsy
Pressure
Optical Imaging
Histology
Color
Prospective Studies
Pathology
Sensitivity and Specificity
Membranes
Neoplasms

Keywords

  • Breast
  • Near-infrared optical absorption imaging

ASJC Scopus subject areas

  • Medicine(all)
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Optical mammography : A new technique for visualizing breast lesions in women presenting non palpable BIRADS 4-5 imaging findings: Preliminary results with radiologic-pathologic correlation. / Athanasiou, Alexandra; Vanel, Daniel; Fournier, Laure; Balleyguier, Corinne.

In: Cancer Imaging, Vol. 7, No. 1, 2007, p. 34-40.

Research output: Contribution to journalArticle

@article{05fa87cf04cb4a01bde8df8244602b78,
title = "Optical mammography: A new technique for visualizing breast lesions in women presenting non palpable BIRADS 4-5 imaging findings: Preliminary results with radiologic-pathologic correlation",
abstract = "The purpose of this prospective study is to determine the diagnostic accuracy of near-infrared breast optical absorption imaging in patients with Breast Imaging Reporting and Data System (BIRADS) 4-5 non-palpable lesions scheduled for biopsy, using pathology after core or excisional biopsy as a reference. The patient's breast was positioned onto a panel of red light-emitting diodes (640nm). A soft membrane was inflated to exert a uniform pressure on the breast. Transmitted light was detected using a CCD camera. The entire acquisition sequence took 1 minute. Image processing generated dynamic images displayed in colour scale, to reveal time-dependent changes in the transmitted light intensity caused by the pressure change. Dynamic curves were classified in two categories: consistently decreasing intensity suspicious for malignancy, and sinusoidal increasing intensity considered as benign. Seventy-eight women consulting for non-palpable breast lesions were initially included in the study. An imaging - histology correlation was obtained for seventy-two patients, the remaining six patients were excluded for technical optical scan reasons. We experienced an overall sensitivity of 73{\%} and specificity of 38{\%}, the false negative results being mainly small size (",
keywords = "Breast, Near-infrared optical absorption imaging",
author = "Alexandra Athanasiou and Daniel Vanel and Laure Fournier and Corinne Balleyguier",
year = "2007",
doi = "10.1102/1470-7330.2007.0006",
language = "English",
volume = "7",
pages = "34--40",
journal = "Cancer Imaging",
issn = "1740-5025",
publisher = "e-med",
number = "1",

}

TY - JOUR

T1 - Optical mammography

T2 - A new technique for visualizing breast lesions in women presenting non palpable BIRADS 4-5 imaging findings: Preliminary results with radiologic-pathologic correlation

AU - Athanasiou, Alexandra

AU - Vanel, Daniel

AU - Fournier, Laure

AU - Balleyguier, Corinne

PY - 2007

Y1 - 2007

N2 - The purpose of this prospective study is to determine the diagnostic accuracy of near-infrared breast optical absorption imaging in patients with Breast Imaging Reporting and Data System (BIRADS) 4-5 non-palpable lesions scheduled for biopsy, using pathology after core or excisional biopsy as a reference. The patient's breast was positioned onto a panel of red light-emitting diodes (640nm). A soft membrane was inflated to exert a uniform pressure on the breast. Transmitted light was detected using a CCD camera. The entire acquisition sequence took 1 minute. Image processing generated dynamic images displayed in colour scale, to reveal time-dependent changes in the transmitted light intensity caused by the pressure change. Dynamic curves were classified in two categories: consistently decreasing intensity suspicious for malignancy, and sinusoidal increasing intensity considered as benign. Seventy-eight women consulting for non-palpable breast lesions were initially included in the study. An imaging - histology correlation was obtained for seventy-two patients, the remaining six patients were excluded for technical optical scan reasons. We experienced an overall sensitivity of 73% and specificity of 38%, the false negative results being mainly small size (

AB - The purpose of this prospective study is to determine the diagnostic accuracy of near-infrared breast optical absorption imaging in patients with Breast Imaging Reporting and Data System (BIRADS) 4-5 non-palpable lesions scheduled for biopsy, using pathology after core or excisional biopsy as a reference. The patient's breast was positioned onto a panel of red light-emitting diodes (640nm). A soft membrane was inflated to exert a uniform pressure on the breast. Transmitted light was detected using a CCD camera. The entire acquisition sequence took 1 minute. Image processing generated dynamic images displayed in colour scale, to reveal time-dependent changes in the transmitted light intensity caused by the pressure change. Dynamic curves were classified in two categories: consistently decreasing intensity suspicious for malignancy, and sinusoidal increasing intensity considered as benign. Seventy-eight women consulting for non-palpable breast lesions were initially included in the study. An imaging - histology correlation was obtained for seventy-two patients, the remaining six patients were excluded for technical optical scan reasons. We experienced an overall sensitivity of 73% and specificity of 38%, the false negative results being mainly small size (

KW - Breast

KW - Near-infrared optical absorption imaging

UR - http://www.scopus.com/inward/record.url?scp=33947537501&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33947537501&partnerID=8YFLogxK

U2 - 10.1102/1470-7330.2007.0006

DO - 10.1102/1470-7330.2007.0006

M3 - Article

C2 - 17339139

AN - SCOPUS:33947537501

VL - 7

SP - 34

EP - 40

JO - Cancer Imaging

JF - Cancer Imaging

SN - 1740-5025

IS - 1

ER -