Optimisation and validation of a remote monitoring system (Onco-TREC) for home-based management of oral anticancer therapies

An Italian multicentre feasibility study

Alessandro Passardi, Mimma Rizzo, Francesca Maines, Carlo Tondini, Alberto Zambelli, Roberto Vespignani, Daniele Andreis, Ilaria Massa, Marco DIanti, Stefano Forti, Enrico Maria Piras, Claudio Eccher

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Introduction: Despite the growing number of oral agents available for cancer treatment, their efficacy may be reduced due to the lack of adherence, inappropriate adverse event self-management and arbitrary dose adjustment. The management of anticancer therapies could exponentially benefit from the introduction of mobile health technologies in a highly integrated electronic oncology system. Methods and analysis: We plan to customise and fine-tune an existing monitoring TreC platform used in different chronic diseases in the oncology setting. This project follows a multistep approach with two major purposes: 1. participatory design techniques driven by Health Literacy and Patient Reported Outcomes principles in order to adapt the system to the oncology setting involving patients and healthcare providers; 2. a prospective training-validation, interventional, non-pharmacological, multicentre study on a series of consecutive patients with cancer (20 and 60 patients in the training and validation steps, respectively) in order to assess system capability, usability and acceptability. The novel Onco-TreC 2.0 is expected to contribute to improving the adherence and safety of cancer care, promoting patient empowerment and patient-doctor communication. Ethics and dissemination: Ethical approval was obtained from the Independent Ethics Committees of the participating institutions (CEIIAV protocol Number 2549/2015; reference Number 1315-PU). Informed consent will be obtained from all study participants. Findings will be disseminated through peer-reviewed journals, conferences and event presentations.

Original languageEnglish
Article numbere014617
JournalBMJ Open
Volume7
Issue number5
DOIs
Publication statusPublished - May 1 2017

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Feasibility Studies
Multicenter Studies
Health Literacy
Patient Participation
Social Adjustment
Neoplasms
Ethics Committees
Biomedical Technology
Telemedicine
Therapeutics
Self Care
Informed Consent
Ethics
Health Personnel
Chronic Disease
Communication
Safety

Keywords

  • adherence
  • home-based healthcare management
  • oral anticancer agents
  • patient empowerment
  • safety

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Optimisation and validation of a remote monitoring system (Onco-TREC) for home-based management of oral anticancer therapies : An Italian multicentre feasibility study. / Passardi, Alessandro; Rizzo, Mimma; Maines, Francesca; Tondini, Carlo; Zambelli, Alberto; Vespignani, Roberto; Andreis, Daniele; Massa, Ilaria; DIanti, Marco; Forti, Stefano; Piras, Enrico Maria; Eccher, Claudio.

In: BMJ Open, Vol. 7, No. 5, e014617, 01.05.2017.

Research output: Contribution to journalArticle

Passardi, Alessandro ; Rizzo, Mimma ; Maines, Francesca ; Tondini, Carlo ; Zambelli, Alberto ; Vespignani, Roberto ; Andreis, Daniele ; Massa, Ilaria ; DIanti, Marco ; Forti, Stefano ; Piras, Enrico Maria ; Eccher, Claudio. / Optimisation and validation of a remote monitoring system (Onco-TREC) for home-based management of oral anticancer therapies : An Italian multicentre feasibility study. In: BMJ Open. 2017 ; Vol. 7, No. 5.
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