Optimisation of brain acquisition MR sequences

A. Crespi, R. G. Pellegrini, N. Paruccini, E. De Ponti, G. Montanari, A. Alfieri, G. Pedroli

Research output: Contribution to journalArticlepeer-review


The optimisation of a MR examination is based on the evaluation of the physical parameters that may influence the quality of diagnostic exams. In particular, we focused our attention on the optimisation of brain acquisition sequences. For this purpose, we analysed how longitudinal relaxation time (T1) and transversal relaxation time (T2) may influence signal values and image contrast. We calculated the T1 and T2 relaxation times of white matter, grey matter and cerebral spinal fluid with a Multi Spin Echo sequence in two healthy patients and the values obtained were compared with the ones in literature. We then calculated contrast to noise curves for the three non- pathological tissues versus Echo time (TE) and Repetition time (TR) and, for practical purposes, we drew iso-contrast curves. Lastly, we evaluated the weighting indexes in T1, T2 and proton density for Spin Echo and Fast Field Echo sequences. The results obtained can be easily understood and applied in clinical routine.

Original languageEnglish
Pages (from-to)222-225
Number of pages4
JournalPhysica Medica
Issue numberSUPPL. 1
Publication statusPublished - 1997


  • Contrast to Noise Ratio
  • MR Imaging
  • Relaxation Times
  • Weighting Index

ASJC Scopus subject areas

  • Biophysics
  • Physics and Astronomy(all)


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