Optimization of antiangiogenic therapy as optimal control problem

Andrzej Swierniak, Grzegorz Gala, Alberto Gandolfi, Alberto D'Onofrio

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A model of antiangiogenic cancer chemotherapy is proposed and analyzed. The model is a modified Hahnfeldt model and the analysis has two goals: first of all we check stability of the equilibrium point of the model to find conditions leading to tumour eradication then we propose an optimization problem and give necessary conditions of its solution.

Original languageEnglish
Title of host publicationProceedings of the Fourth IASTED International Conference on Biomechanics, BioMech 2006
Pages56-59
Number of pages4
Publication statusPublished - 2006
Event4th IASTED International Conference on Biomechanics, BioMech 2006 - Palma de Mallorca, Spain
Duration: Aug 28 2006Aug 29 2006

Other

Other4th IASTED International Conference on Biomechanics, BioMech 2006
CountrySpain
CityPalma de Mallorca
Period8/28/068/29/06

Keywords

  • Angiogenesis
  • Anticancer therapy
  • Drug delivery
  • Modeling
  • Simulation
  • Systems and control

ASJC Scopus subject areas

  • Biophysics
  • Mechanical Engineering

Fingerprint Dive into the research topics of 'Optimization of antiangiogenic therapy as optimal control problem'. Together they form a unique fingerprint.

  • Cite this

    Swierniak, A., Gala, G., Gandolfi, A., & D'Onofrio, A. (2006). Optimization of antiangiogenic therapy as optimal control problem. In Proceedings of the Fourth IASTED International Conference on Biomechanics, BioMech 2006 (pp. 56-59)