Optimizing craniospinal radiotherapy delivery in a pediatric patient affected by supratentorial PNET: A case report

Maurizio Mascarin, Annalisa Drigo, Andrea Dassie, Marco Gigante, Giovanni Franchin, Giovanna Sartor, Mauro G. Trovò

Research output: Contribution to journalArticle


New advances in radiation therapy for children allow increased conformability and reduced doses to non-target tissues. We report our experience in treating a 4-year-old child with craniospinal tomotherapy after surgery of the primary tumor, a supratentorial primitive neuroectodermal tumor. The tomotherapy plan was compared with conventional craniospinal irradiation, 3D conformal radiation therapy, and intensity-modulated radiation therapy plans. The possible disadvantages of tomotherapy related to the radiation dose to organs at risk, treatment planning, and anesthesia should be carefully considered as the use of the technique is not suggested in a general manner, but selectively, in critical pediatric radiotherapy cases.

Original languageEnglish
Pages (from-to)316-321
Number of pages6
Issue number2
Publication statusPublished - Mar 2010



  • Craniospinal irradiation
  • IMRT
  • Integral dose
  • Pediatric tumors
  • Tomotherapy

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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