Optimizing the Use of Available Lungs

Daniela Peritore, Lucia Rizzato, Silvia Trapani, Vincenzo Emiliano Morabito, Pamela Fiaschetti, Anna Rita Cacciotti, Antonino Montemurro, Elena Del Sordo, Andrea Ricci, Alessandro Nanni Costa

Research output: Contribution to journalArticle

Abstract

Background Organ transplantation, the treatment of choice in organ failure, is penalized by the lack of organs. Because the increase in the number of donors is not proportional throughout the different age groups, there is no increase in lung transplantations. The aim of this work was to analyze the use of available lungs and evaluate strategies that may help increase transplantations. Methods We analyzed the activity of lung transplantation in 2015, divided into various allocation programs. We also examined the surplus organs, in particular, their origin, their destination, their offer's outcome, the characteristics of the donor and the proposed organ, and the reasons for rejection. Results In 2015, 112 lung transplantations were performed: 66 (68.9%) with regional organs, 46 (41.1%) with extraregional organs; 21 (45.6%) of these were allocated as emergencies/return, and 25 (54.4%) as surplus (19 in the North macroarea, 6 in the South macroarea). The number of surplus lungs was 148: 67 from the North macroarea, 71 from the South macroarea, and 10 from abroad. No organ procured in the North macroarea was transplanted in the South macroarea, whereas 6 lungs coming from the South macroarea were transplanted in the North. Conclusions The acceptance criteria are not the same in different transplant centers and they include not only clinical parameters, but also ischemia time and composition of the waiting list at the time of the offer, quality and accessibility of the intensive care units where the donor is located, and organizational reasons. Offering organs which can not be transplanted within the region to other centers, without clinical foreclosures is a system that increases transplant activities by maximizing the available resources.

Original languageEnglish
Pages (from-to)692-694
Number of pages3
JournalTransplantation Proceedings
Volume49
Issue number4
DOIs
Publication statusPublished - May 1 2017

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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    Peritore, D., Rizzato, L., Trapani, S., Morabito, V. E., Fiaschetti, P., Cacciotti, A. R., Montemurro, A., Del Sordo, E., Ricci, A., & Nanni Costa, A. (2017). Optimizing the Use of Available Lungs. Transplantation Proceedings, 49(4), 692-694. https://doi.org/10.1016/j.transproceed.2017.02.041