Abstract
The aim was to measure the ionic fluoride concentration in maternal plasma and in amniotic fluid after oral administration of different doses of sodium fluoride (NaF) to 121 pregnant women. They were divided into six groups, according to the dose administered; 0 for the control group and 0.25, 0.50, 0.75, 1.00 or 1.25 mg of F- for the others. The subjects were instructed to take the corresponding NaF dose both 24 and 3 h before amniocentesis. Amniotic fluid (5 ml) and venous blood (5 ml) were obtained from each subject. Ionic fluoride concentration was measured with an expanded-scale potentiometer and a selective fluoride electrode. The results showed that F- concentration in amniotic fluid and, presumably, in fetal circulation, was not significantly different in groups taking 0.25, 0.50, 0.75 or 1.00 mg/day of F-. The F- concentration in amniotic fluid of the 1.25 mg/day group was, however, significantly higher than in all the other groups.
| Original language | English |
|---|---|
| Pages (from-to) | 991-994 |
| Number of pages | 4 |
| Journal | Archives of Oral Biology |
| Volume | 39 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 1994 |
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Keywords
- amniotic fluid
- fluoride
- placenta
- plasma
ASJC Scopus subject areas
- Dentistry(all)
Cite this
Oral administration of fluoride in pregnant women, and the relation between concentration in maternal plasma and in amniotic fluid. / Brambilla, E.; Belluomo, G.; Malerba, A.; Buscaglia, M.; Strohmenger, L.
In: Archives of Oral Biology, Vol. 39, No. 11, 1994, p. 991-994.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Oral administration of fluoride in pregnant women, and the relation between concentration in maternal plasma and in amniotic fluid
AU - Brambilla, E.
AU - Belluomo, G.
AU - Malerba, A.
AU - Buscaglia, M.
AU - Strohmenger, L.
PY - 1994
Y1 - 1994
N2 - The aim was to measure the ionic fluoride concentration in maternal plasma and in amniotic fluid after oral administration of different doses of sodium fluoride (NaF) to 121 pregnant women. They were divided into six groups, according to the dose administered; 0 for the control group and 0.25, 0.50, 0.75, 1.00 or 1.25 mg of F- for the others. The subjects were instructed to take the corresponding NaF dose both 24 and 3 h before amniocentesis. Amniotic fluid (5 ml) and venous blood (5 ml) were obtained from each subject. Ionic fluoride concentration was measured with an expanded-scale potentiometer and a selective fluoride electrode. The results showed that F- concentration in amniotic fluid and, presumably, in fetal circulation, was not significantly different in groups taking 0.25, 0.50, 0.75 or 1.00 mg/day of F-. The F- concentration in amniotic fluid of the 1.25 mg/day group was, however, significantly higher than in all the other groups.
AB - The aim was to measure the ionic fluoride concentration in maternal plasma and in amniotic fluid after oral administration of different doses of sodium fluoride (NaF) to 121 pregnant women. They were divided into six groups, according to the dose administered; 0 for the control group and 0.25, 0.50, 0.75, 1.00 or 1.25 mg of F- for the others. The subjects were instructed to take the corresponding NaF dose both 24 and 3 h before amniocentesis. Amniotic fluid (5 ml) and venous blood (5 ml) were obtained from each subject. Ionic fluoride concentration was measured with an expanded-scale potentiometer and a selective fluoride electrode. The results showed that F- concentration in amniotic fluid and, presumably, in fetal circulation, was not significantly different in groups taking 0.25, 0.50, 0.75 or 1.00 mg/day of F-. The F- concentration in amniotic fluid of the 1.25 mg/day group was, however, significantly higher than in all the other groups.
KW - amniotic fluid
KW - fluoride
KW - placenta
KW - plasma
UR - http://www.scopus.com/inward/record.url?scp=0028541084&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028541084&partnerID=8YFLogxK
U2 - 10.1016/0003-9969(94)90084-1
DO - 10.1016/0003-9969(94)90084-1
M3 - Article
VL - 39
SP - 991
EP - 994
JO - Archives of Oral Biology
JF - Archives of Oral Biology
SN - 0003-9969
IS - 11
ER -