Oral cavity and base of the tongue tumors. Correlation between clinical, MRI and pathological staging of primary tumor

Antonello Vidiri, P. Ruscito, B. Pichi, R. Pellini, R. Covello, I. Sperduti, S. Di Giovanni, G. Spriano, M. Crecco

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The diagnosis of oral cavity and oropharyngeal tumors can be obtained through clinical examination and biopsy. CT and MRI can then be used to define the extension of the disease. The aim of this study was to define the accuracy of clinical and MRI T staging of oral cavity and base of the tongue tumors and correlate the results with pathological data. Mandibular involvement, in a subgroup of patients, was determined and sensitivity, specificity, accuracy and positive and negative predictive values were evaluated. Fifty-nine patients affected by squamous cell carcinoma and 1 case of adenoido-cystic carcinoma were examined by means of a superconductive MR unit, using SE T1, and fat-suppressed T2 weighted sequences before contrast medium infusion. SE T1 and T1 fat-suppressed sequences after gadolinium-DTPA infusion were used. T stage accuracy of both clinical examination and MRI were found to be respectively 62% (k 0.459) and 82% (k 0.775). The sensitivity, specificity and accuracy of MRI in the detection of mandibular involvement were 94.1%, 60% and 81.5%, while the positive and negative predictive values were 80% and 85.7%, respectively. The sensitivity, specificity and accuracy of clinical examination in the detection of mandibular involvement were 100%, 30% and 74.1%, while the positive and negative predictive values were 70.8% and 100%. In the present study, MRI was seen to be an adequate technique for the assessment of oral cavity malignancies, in the evaluation of depth invasion, presence and extension of mandibular involvement.

Original languageEnglish
Pages (from-to)575-582
Number of pages8
JournalJournal of Experimental and Clinical Cancer Research
Volume26
Issue number4
Publication statusPublished - Dec 2007

Fingerprint

Neoplasm Staging
Tongue
Mouth
Sensitivity and Specificity
Fats
Neoplasms
Gadolinium DTPA
Contrast Media
Squamous Cell Carcinoma
Carcinoma
Biopsy

Keywords

  • Base of the tongue imaging
  • Magnetic Resonance Imaging comparative studies
  • Mandible MRI
  • Oral cavity imaging

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Oral cavity and base of the tongue tumors. Correlation between clinical, MRI and pathological staging of primary tumor. / Vidiri, Antonello; Ruscito, P.; Pichi, B.; Pellini, R.; Covello, R.; Sperduti, I.; Di Giovanni, S.; Spriano, G.; Crecco, M.

In: Journal of Experimental and Clinical Cancer Research, Vol. 26, No. 4, 12.2007, p. 575-582.

Research output: Contribution to journalArticle

Vidiri, A, Ruscito, P, Pichi, B, Pellini, R, Covello, R, Sperduti, I, Di Giovanni, S, Spriano, G & Crecco, M 2007, 'Oral cavity and base of the tongue tumors. Correlation between clinical, MRI and pathological staging of primary tumor', Journal of Experimental and Clinical Cancer Research, vol. 26, no. 4, pp. 575-582.
Vidiri, Antonello ; Ruscito, P. ; Pichi, B. ; Pellini, R. ; Covello, R. ; Sperduti, I. ; Di Giovanni, S. ; Spriano, G. ; Crecco, M. / Oral cavity and base of the tongue tumors. Correlation between clinical, MRI and pathological staging of primary tumor. In: Journal of Experimental and Clinical Cancer Research. 2007 ; Vol. 26, No. 4. pp. 575-582.
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