Oral chemotherapy and patient perspective in solid tumors: A national survey by the Italian association of medical oncology

Gaetano Aurilio, Stefania Gori, Franco Noie, Giancarlo Pruned, Francesca Coati, Valter Torri, Gianluigi Lunardi, Francesco Atzori, Nicla La Verde, Giuseppe Luigi Banna, A. Rossi, Lucia Del Mastro, Francesca Di Fabio, Maria Marcon, V. Gebbia, Fotios Loupakis, Laura Orlando, Libero Ciuffreda, Placido Amadio, Gabriele LuppiStefania Redana, G. Filippelli, Anna Lisa Gentile, Elena Collovà

Research output: Contribution to journalArticle

Abstract

Aim: To assess patient perception toward oral chemotherapy for solid tumors, the Italian Association of Medical Oncology performed a large multi-institutional national survey. Methods: A 17-item anonymous questionnaire including 7 general and 10 investigational questions with free-text, single-choice, or multiple-choice answers was administered. Analysis of response distribution according to predefined factors was described by summary measures and conducted by χ2 test and other nonparametric tests. Results: From January to June 2010, 581 patients completed the questionnaire; data of 404 patients constituted the final study sample. Three groups could be distinguished according to treatment: IV chemotherapy (IV group, n = 313), oral chemotherapy (oral group, n = 48), or combined therapy (combined group, n = 43). Thirty-one (72%) patients in the combined group and 187 (60%) in the IV group expressed preference for oral therapy (p = 0.028). Limitations in family and work commitment were more frequently perceived by patients on IV than oral chemotherapy (147 (47%) vs 14 (29%) patients, p

Original languageEnglish
Pages (from-to)108-113
Number of pages6
JournalTumori
Volume102
Issue number1
DOIs
Publication statusPublished - Jan 1 2016

Keywords

  • IV chemotherapy
  • Oral chemotherapy
  • Patient perspective
  • Questionnaire
  • Treatment

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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    Aurilio, G., Gori, S., Noie, F., Pruned, G., Coati, F., Torri, V., Lunardi, G., Atzori, F., La Verde, N., Banna, G. L., Rossi, A., Del Mastro, L., Di Fabio, F., Marcon, M., Gebbia, V., Loupakis, F., Orlando, L., Ciuffreda, L., Amadio, P., ... Collovà, E. (2016). Oral chemotherapy and patient perspective in solid tumors: A national survey by the Italian association of medical oncology. Tumori, 102(1), 108-113. https://doi.org/10.5301/tj.5000383