Oral CorticoSteroid sparing with biologics in severe asthma:: A remark of the Severe Asthma Network in Italy (SANI)

G.W. Canonica; F. Blasi; P. Paggiaro; G. Senna; G. Passalacqua; A. Spanevello; S. Aliberti; D. Bagnasco; M. Bonavia; M. Bonini; L. Brussino; C. Bucca; M.F. Caiaffa; C. Calabrese; G. Camiciottoli; M. Caminati; G.E. Carpagnano; C. Caruso; S. Centanni; M.E. Conte; A.G. Corsico; L. Cosmi; M.T. Costantino; N. Crimi; S. D'Alò; M. D'Amato; S. Del Giacco; A. Farsi; E. Favero; M.P. Foschino Barbaro; G. Guarnieri; G. Guida; M. Latorre; S. Lo Cicero; C. Lombardi; L. Macchia; F. Mazza; F. Menzella; M. Milanese; M. Montagni; P. Montuschi; E. Nucera; R. Parente; V. Patella; G. Pelaia; L. Pini; F. Puggioni; L. Ricciardi; F.L.M. Ricciardolo; L. Richeldi; E. Ridolo; G. Rolla; P. Santus; N. Scichilone; G. Spadaro; A. Vianello; V. Viviano; M.R. Yacoub; M.C. Zappa; E. Heffler; SANI (Severe Asthma Network Italy)

doi:10.1016/j.waojou.2020.100464

Oral CorticoSteroid sparing with biologics in severe asthma: A remark of the Severe Asthma Network in Italy (SANI)

G.W. Canonica, F. Blasi, P. Paggiaro, G. Senna, G. Passalacqua, A. Spanevello, S. Aliberti, D. Bagnasco, M. Bonavia, M. Bonini, L. Brussino, C. Bucca, M.F. Caiaffa, C. Calabrese, G. Camiciottoli, M. Caminati, G.E. Carpagnano, C. Caruso, S. Centanni, M.E. ConteA.G. Corsico, L. Cosmi, M.T. Costantino, N. Crimi, S. D'Alò, M. D'Amato, S. Del Giacco, A. Farsi, E. Favero, M.P. Foschino Barbaro, G. Guarnieri, G. Guida, M. Latorre, S. Lo Cicero, C. Lombardi, L. Macchia, F. Mazza, F. Menzella, M. Milanese, M. Montagni, P. Montuschi, E. Nucera, R. Parente, V. Patella, G. Pelaia, L. Pini, F. Puggioni, L. Ricciardi, F.L.M. Ricciardolo, L. Richeldi, E. Ridolo, G. Rolla, P. Santus, N. Scichilone, G. Spadaro, A. Vianello, V. Viviano, M.R. Yacoub, M.C. Zappa, E. Heffler, SANI (Severe Asthma Network Italy)

Research output: Contribution to journal › Article › peer-review

Abstract

According to the data derived from several national and international registries, including SANI (Severe Asthma Network Italy), and considering the strong impact that frequent or regular use of oral corticosteroid has on quality of life (QoL) of severe asthmatics, as well as on the costs for managing corticosteroid-related diseases, oral corticosteroid sparing up to withdrawal should be considered a primary outcome in the management of severe asthma. New biologics have clearly demonstrated that this effect is possible, with concomitant reduction in the rate of exacerbations and in symptom control. Then, there is no reason for using so frequently oral corticosteroid before having explored all alternatives currently available for a large part of severe asthmatics. © 2020 The Authors

Original language	English
Article number	100464
Journal	World Allergy Organization Journal
Volume	13
Issue number	10
DOIs	https://doi.org/10.1016/j.waojou.2020.100464
Publication status	Published - 2020

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10.1016/j.waojou.2020.100464

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85091219259&doi=10.1016%2fj.waojou.2020.100464&partnerID=40&md5=ed8165eca34dcc53d11dcbfebb6f8783

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Canonica, G. W., Blasi, F., Paggiaro, P., Senna, G., Passalacqua, G., Spanevello, A., Aliberti, S., Bagnasco, D., Bonavia, M., Bonini, M., Brussino, L., Bucca, C., Caiaffa, M. F., Calabrese, C., Camiciottoli, G., Caminati, M., Carpagnano, G. E., Caruso, C., Centanni, S., ... Italy), SANI. (2020). Oral CorticoSteroid sparing with biologics in severe asthma: A remark of the Severe Asthma Network in Italy (SANI). World Allergy Organization Journal, 13(10), [100464]. https://doi.org/10.1016/j.waojou.2020.100464

Oral CorticoSteroid sparing with biologics in severe asthma: A remark of the Severe Asthma Network in Italy (SANI). / Canonica, G.W.; Blasi, F.; Paggiaro, P.; Senna, G.; Passalacqua, G.; Spanevello, A.; Aliberti, S.; Bagnasco, D.; Bonavia, M.; Bonini, M.; Brussino, L.; Bucca, C.; Caiaffa, M.F.; Calabrese, C.; Camiciottoli, G.; Caminati, M.; Carpagnano, G.E.; Caruso, C.; Centanni, S.; Conte, M.E.; Corsico, A.G.; Cosmi, L.; Costantino, M.T.; Crimi, N.; D'Alò, S.; D'Amato, M.; Del Giacco, S.; Farsi, A.; Favero, E.; Foschino Barbaro, M.P.; Guarnieri, G.; Guida, G.; Latorre, M.; Lo Cicero, S.; Lombardi, C.; Macchia, L.; Mazza, F.; Menzella, F.; Milanese, M.; Montagni, M.; Montuschi, P.; Nucera, E.; Parente, R.; Patella, V.; Pelaia, G.; Pini, L.; Puggioni, F.; Ricciardi, L.; Ricciardolo, F.L.M.; Richeldi, L.; Ridolo, E.; Rolla, G.; Santus, P.; Scichilone, N.; Spadaro, G.; Vianello, A.; Viviano, V.; Yacoub, M.R.; Zappa, M.C.; Heffler, E.; Italy), SANI (Severe Asthma Network.

In: World Allergy Organization Journal, Vol. 13, No. 10, 100464, 2020.

Research output: Contribution to journal › Article › peer-review

Canonica, GW , Blasi, F, Paggiaro, P, Senna, G, Passalacqua, G, Spanevello, A , Aliberti, S, Bagnasco, D, Bonavia, M, Bonini, M, Brussino, L, Bucca, C, Caiaffa, MF, Calabrese, C, Camiciottoli, G, Caminati, M, Carpagnano, GE, Caruso, C, Centanni, S, Conte, ME, Corsico, AG, Cosmi, L, Costantino, MT, Crimi, N, D'Alò, S, D'Amato, M, Del Giacco, S, Farsi, A, Favero, E, Foschino Barbaro, MP, Guarnieri, G, Guida, G, Latorre, M, Lo Cicero, S , Lombardi, C, Macchia, L, Mazza, F, Menzella, F, Milanese, M, Montagni, M, Montuschi, P, Nucera, E, Parente, R, Patella, V, Pelaia, G, Pini, L, Puggioni, F, Ricciardi, L, Ricciardolo, FLM, Richeldi, L, Ridolo, E, Rolla, G, Santus, P, Scichilone, N, Spadaro, G, Vianello, A, Viviano, V, Yacoub, MR, Zappa, MC, Heffler, E & Italy), SANI 2020, 'Oral CorticoSteroid sparing with biologics in severe asthma: A remark of the Severe Asthma Network in Italy (SANI)', World Allergy Organization Journal, vol. 13, no. 10, 100464. https://doi.org/10.1016/j.waojou.2020.100464

Canonica, G.W. ; Blasi, F. ; Paggiaro, P. ; Senna, G. ; Passalacqua, G. ; Spanevello, A. ; Aliberti, S. ; Bagnasco, D. ; Bonavia, M. ; Bonini, M. ; Brussino, L. ; Bucca, C. ; Caiaffa, M.F. ; Calabrese, C. ; Camiciottoli, G. ; Caminati, M. ; Carpagnano, G.E. ; Caruso, C. ; Centanni, S. ; Conte, M.E. ; Corsico, A.G. ; Cosmi, L. ; Costantino, M.T. ; Crimi, N. ; D'Alò, S. ; D'Amato, M. ; Del Giacco, S. ; Farsi, A. ; Favero, E. ; Foschino Barbaro, M.P. ; Guarnieri, G. ; Guida, G. ; Latorre, M. ; Lo Cicero, S. ; Lombardi, C. ; Macchia, L. ; Mazza, F. ; Menzella, F. ; Milanese, M. ; Montagni, M. ; Montuschi, P. ; Nucera, E. ; Parente, R. ; Patella, V. ; Pelaia, G. ; Pini, L. ; Puggioni, F. ; Ricciardi, L. ; Ricciardolo, F.L.M. ; Richeldi, L. ; Ridolo, E. ; Rolla, G. ; Santus, P. ; Scichilone, N. ; Spadaro, G. ; Vianello, A. ; Viviano, V. ; Yacoub, M.R. ; Zappa, M.C. ; Heffler, E. ; Italy), SANI (Severe Asthma Network. / Oral CorticoSteroid sparing with biologics in severe asthma: A remark of the Severe Asthma Network in Italy (SANI). In: World Allergy Organization Journal. 2020 ; Vol. 13, No. 10.

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title = "Oral CorticoSteroid sparing with biologics in severe asthma:: A remark of the Severe Asthma Network in Italy (SANI)",

abstract = "According to the data derived from several national and international registries, including SANI (Severe Asthma Network Italy), and considering the strong impact that frequent or regular use of oral corticosteroid has on quality of life (QoL) of severe asthmatics, as well as on the costs for managing corticosteroid-related diseases, oral corticosteroid sparing up to withdrawal should be considered a primary outcome in the management of severe asthma. New biologics have clearly demonstrated that this effect is possible, with concomitant reduction in the rate of exacerbations and in symptom control. Then, there is no reason for using so frequently oral corticosteroid before having explored all alternatives currently available for a large part of severe asthmatics. {\textcopyright} 2020 The Authors",

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AU - Senna, G.

AU - Passalacqua, G.

AU - Spanevello, A.

AU - Aliberti, S.

AU - Bagnasco, D.

AU - Bonavia, M.

AU - Bonini, M.

AU - Brussino, L.

AU - Bucca, C.

AU - Caiaffa, M.F.

AU - Calabrese, C.

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AU - Del Giacco, S.

AU - Farsi, A.

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AU - Foschino Barbaro, M.P.

AU - Guarnieri, G.

AU - Guida, G.

AU - Latorre, M.

AU - Lo Cicero, S.

AU - Lombardi, C.

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AU - Mazza, F.

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AB - According to the data derived from several national and international registries, including SANI (Severe Asthma Network Italy), and considering the strong impact that frequent or regular use of oral corticosteroid has on quality of life (QoL) of severe asthmatics, as well as on the costs for managing corticosteroid-related diseases, oral corticosteroid sparing up to withdrawal should be considered a primary outcome in the management of severe asthma. New biologics have clearly demonstrated that this effect is possible, with concomitant reduction in the rate of exacerbations and in symptom control. Then, there is no reason for using so frequently oral corticosteroid before having explored all alternatives currently available for a large part of severe asthmatics. © 2020 The Authors

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DO - 10.1016/j.waojou.2020.100464

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VL - 13

JO - World Allergy Organization Journal

JF - World Allergy Organization Journal

SN - 1939-4551

IS - 10

M1 - 100464

ER -

Oral CorticoSteroid sparing with biologics in severe asthma: A remark of the Severe Asthma Network in Italy (SANI)

Abstract

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