Oral lichenoid tissue reactions

Diagnosis and classification

Ahmed Salih Khudhur, Giovanni Di Zenzo, Marco Carrozzo

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

The concept of lichenoid tissue reaction/interface dermatitis was introduced in dermatology to define a number of diverse inflammatory skin diseases linked together by the presence of common histopathological features. Similarly to the skin, the oral mucosa is affected by a variety of oral lichenoid lesions. Oral LTRs (OLTRs) include: oral lichen planus; oral lichenoid contact lesion; oral lichenoid drug reaction; oral lichenoid lesions of graft-versus-host disease; oral discoid lupus erythematosus; oral lesions of systemic lupus erythematosus; erythema multiforme; paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome; chronic ulcerative stomatitis and lichen planus pemphigoid. Traditionally, diagnosis of OLTRs relies on clinical and histological correlation but in several instances this approach fails to provide a reliable diagnosis. Inclusion of molecular techniques may refine our ability to differentiate OLTRs.

Original languageEnglish
Pages (from-to)169-184
Number of pages16
JournalExpert Review of Molecular Diagnostics
Volume14
Issue number2
DOIs
Publication statusPublished - Mar 2014

Fingerprint

Necrotizing Ulcerative Gingivitis
Discoid Lupus Erythematosus
Oral Lichen Planus
Erythema Multiforme
Oral Diagnosis
Bullous Pemphigoid
Lichen Planus
Pemphigus
Mouth Mucosa
Graft vs Host Disease
Dermatitis
Dermatology
Skin Diseases
Systemic Lupus Erythematosus
Skin
Pharmaceutical Preparations

Keywords

  • chronic ulcerative stomatitis
  • discoid lupus erythematosus
  • erythema multiforme
  • graft-versus-host disease
  • lichen planus
  • lichen planus pemphigoid
  • lichenoid lesions
  • oral lichen planus
  • paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome
  • systemic lupus erythematosus

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Pathology and Forensic Medicine

Cite this

Oral lichenoid tissue reactions : Diagnosis and classification. / Khudhur, Ahmed Salih; Di Zenzo, Giovanni; Carrozzo, Marco.

In: Expert Review of Molecular Diagnostics, Vol. 14, No. 2, 03.2014, p. 169-184.

Research output: Contribution to journalArticle

Khudhur, Ahmed Salih ; Di Zenzo, Giovanni ; Carrozzo, Marco. / Oral lichenoid tissue reactions : Diagnosis and classification. In: Expert Review of Molecular Diagnostics. 2014 ; Vol. 14, No. 2. pp. 169-184.
@article{c275a37998f54f598c1fb2d1cb027293,
title = "Oral lichenoid tissue reactions: Diagnosis and classification",
abstract = "The concept of lichenoid tissue reaction/interface dermatitis was introduced in dermatology to define a number of diverse inflammatory skin diseases linked together by the presence of common histopathological features. Similarly to the skin, the oral mucosa is affected by a variety of oral lichenoid lesions. Oral LTRs (OLTRs) include: oral lichen planus; oral lichenoid contact lesion; oral lichenoid drug reaction; oral lichenoid lesions of graft-versus-host disease; oral discoid lupus erythematosus; oral lesions of systemic lupus erythematosus; erythema multiforme; paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome; chronic ulcerative stomatitis and lichen planus pemphigoid. Traditionally, diagnosis of OLTRs relies on clinical and histological correlation but in several instances this approach fails to provide a reliable diagnosis. Inclusion of molecular techniques may refine our ability to differentiate OLTRs.",
keywords = "chronic ulcerative stomatitis, discoid lupus erythematosus, erythema multiforme, graft-versus-host disease, lichen planus, lichen planus pemphigoid, lichenoid lesions, oral lichen planus, paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome, systemic lupus erythematosus",
author = "Khudhur, {Ahmed Salih} and {Di Zenzo}, Giovanni and Marco Carrozzo",
year = "2014",
month = "3",
doi = "10.1586/14737159.2014.888953",
language = "English",
volume = "14",
pages = "169--184",
journal = "Expert Review of Molecular Diagnostics",
issn = "1473-7159",
publisher = "Expert Reviews Ltd.",
number = "2",

}

TY - JOUR

T1 - Oral lichenoid tissue reactions

T2 - Diagnosis and classification

AU - Khudhur, Ahmed Salih

AU - Di Zenzo, Giovanni

AU - Carrozzo, Marco

PY - 2014/3

Y1 - 2014/3

N2 - The concept of lichenoid tissue reaction/interface dermatitis was introduced in dermatology to define a number of diverse inflammatory skin diseases linked together by the presence of common histopathological features. Similarly to the skin, the oral mucosa is affected by a variety of oral lichenoid lesions. Oral LTRs (OLTRs) include: oral lichen planus; oral lichenoid contact lesion; oral lichenoid drug reaction; oral lichenoid lesions of graft-versus-host disease; oral discoid lupus erythematosus; oral lesions of systemic lupus erythematosus; erythema multiforme; paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome; chronic ulcerative stomatitis and lichen planus pemphigoid. Traditionally, diagnosis of OLTRs relies on clinical and histological correlation but in several instances this approach fails to provide a reliable diagnosis. Inclusion of molecular techniques may refine our ability to differentiate OLTRs.

AB - The concept of lichenoid tissue reaction/interface dermatitis was introduced in dermatology to define a number of diverse inflammatory skin diseases linked together by the presence of common histopathological features. Similarly to the skin, the oral mucosa is affected by a variety of oral lichenoid lesions. Oral LTRs (OLTRs) include: oral lichen planus; oral lichenoid contact lesion; oral lichenoid drug reaction; oral lichenoid lesions of graft-versus-host disease; oral discoid lupus erythematosus; oral lesions of systemic lupus erythematosus; erythema multiforme; paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome; chronic ulcerative stomatitis and lichen planus pemphigoid. Traditionally, diagnosis of OLTRs relies on clinical and histological correlation but in several instances this approach fails to provide a reliable diagnosis. Inclusion of molecular techniques may refine our ability to differentiate OLTRs.

KW - chronic ulcerative stomatitis

KW - discoid lupus erythematosus

KW - erythema multiforme

KW - graft-versus-host disease

KW - lichen planus

KW - lichen planus pemphigoid

KW - lichenoid lesions

KW - oral lichen planus

KW - paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome

KW - systemic lupus erythematosus

UR - http://www.scopus.com/inward/record.url?scp=84894597034&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84894597034&partnerID=8YFLogxK

U2 - 10.1586/14737159.2014.888953

DO - 10.1586/14737159.2014.888953

M3 - Article

VL - 14

SP - 169

EP - 184

JO - Expert Review of Molecular Diagnostics

JF - Expert Review of Molecular Diagnostics

SN - 1473-7159

IS - 2

ER -