Terapia steroidea delle epilessie farmacoresistenti: I risultati ottenuti con cicli di prednisone

Translated title of the contribution: Oral steroids in childhood intractable epilepsy: Results obtained with prednisone cycles

S. Ricci, M. S. Vari, M. Mancardi, M. P. Baglietto, R. Gaggero

Research output: Contribution to journalArticle

Abstract

Oral steroids besides ACTH, are extensively used in childhood intractable epilepsy, but therapy schedules are variable and the results are not concordant. We present an open study on 20 cases treated in a homogenous way: prednisone from 2 mg/kg/day to 0,5 mg/kg/day for 4-7 mths. The cases were affected overall by CSWS and epileptic encephalopathy. A complete clinical response was obtained in 10 cases, a reduction > 50% in other 8. A remission of EEG abnormalities in 5 and a reduction > 50% in 13. All the moderate side effects observed in 12 cases were reversible. Effectiveness and tolerability of this steroids schedule are confirmed.

Original languageItalian
Pages (from-to)257-258
Number of pages2
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number136-137
Publication statusPublished - May 2008

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Prednisone
Appointments and Schedules
Steroids
Brain Diseases
Adrenocorticotropic Hormone
Electroencephalography
Drug Resistant Epilepsy
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Terapia steroidea delle epilessie farmacoresistenti : I risultati ottenuti con cicli di prednisone. / Ricci, S.; Vari, M. S.; Mancardi, M.; Baglietto, M. P.; Gaggero, R.

In: Bollettino - Lega Italiana contro l'Epilessia, No. 136-137, 05.2008, p. 257-258.

Research output: Contribution to journalArticle

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