Sarcoma granulocitico dell'orbita

Case report

Translated title of the contribution: Orbital granulocytic sarcoma: Case report

Letterio Morabito, Riccardo Antonio Ricciuti, Roberto Trignani, Lucia Innocenti, Emilio Agostini, Massimo Vissani, Samantha Massaccesi, Marina Scarpelli, Attilio Olivieri, Moira Lucesole, Pierto Leoni

Research output: Contribution to journalArticle

Abstract

Granulocytic sarcoma is a rare solid tumor formed by primitive myeloid cells. It represents an expression of acute myeloid leukaemia or, less frequently, of chronic ones or of myeloproliferative diseases. Besides, it can appears some weeks or years before the development of such diseases. The authors describe the case of an orbital chloroma in a patient with a clinical history of progressive exophthalmos and diplopia, without signs and symptoms in relation to a systemic disease. The lesion was studied by CT and MRI and then was operated; histopathological diagnosis was of orbital granulocytic sarcoma. After the patient underwent molecular investigations on peripherical blood and bone marrow biopsy which allowed to do the diagnosis of a minor myeloproliferative syndrome. Therefore, the patient was submitted to a chemotherapeutic treatment in according of ICE scheme. At 1-year clinical and radiological follow-up, there was no evidence of local regrowth of disease. The authors explain clinical aspects and compare them with literature data; they outline the importance of an early diagnosis to begin an aggressive chemotherapeutic regimen above all in the cases where sarcoma appears before the development of myeloproliferative disease.

Original languageItalian
Pages (from-to)361-364
Number of pages4
JournalRivista di Neurobiologia
Volume47
Issue number5
Publication statusPublished - 2001

Fingerprint

Myeloid Sarcoma
Exophthalmos
Diplopia
Myeloid Cells
Acute Myeloid Leukemia
Sarcoma
Signs and Symptoms
Early Diagnosis
Bone Marrow
Biopsy
Neoplasms

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Morabito, L., Ricciuti, R. A., Trignani, R., Innocenti, L., Agostini, E., Vissani, M., ... Leoni, P. (2001). Sarcoma granulocitico dell'orbita: Case report. Rivista di Neurobiologia, 47(5), 361-364.

Sarcoma granulocitico dell'orbita : Case report. / Morabito, Letterio; Ricciuti, Riccardo Antonio; Trignani, Roberto; Innocenti, Lucia; Agostini, Emilio; Vissani, Massimo; Massaccesi, Samantha; Scarpelli, Marina; Olivieri, Attilio; Lucesole, Moira; Leoni, Pierto.

In: Rivista di Neurobiologia, Vol. 47, No. 5, 2001, p. 361-364.

Research output: Contribution to journalArticle

Morabito, L, Ricciuti, RA, Trignani, R, Innocenti, L, Agostini, E, Vissani, M, Massaccesi, S, Scarpelli, M, Olivieri, A, Lucesole, M & Leoni, P 2001, 'Sarcoma granulocitico dell'orbita: Case report', Rivista di Neurobiologia, vol. 47, no. 5, pp. 361-364.
Morabito L, Ricciuti RA, Trignani R, Innocenti L, Agostini E, Vissani M et al. Sarcoma granulocitico dell'orbita: Case report. Rivista di Neurobiologia. 2001;47(5):361-364.
Morabito, Letterio ; Ricciuti, Riccardo Antonio ; Trignani, Roberto ; Innocenti, Lucia ; Agostini, Emilio ; Vissani, Massimo ; Massaccesi, Samantha ; Scarpelli, Marina ; Olivieri, Attilio ; Lucesole, Moira ; Leoni, Pierto. / Sarcoma granulocitico dell'orbita : Case report. In: Rivista di Neurobiologia. 2001 ; Vol. 47, No. 5. pp. 361-364.
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