Orbital osteoclastoma of apparent extraskeletal origin in a pagetic patient: A case report

Irene Pecorella, Antonio Ciardi, Giorgio Amadeo, Andrea Baiocchini, Angela Marasco, Ugo Di Tondo

Research output: Contribution to journalArticle

Abstract

A large mass in the right orbit, causing proptosis, ptosis of the right upper eyelid, and limitation to eye movements, was surgically removed from a 51-year-old woman suffering from Paget's bone disease (PBD). Histologically, a giant cell tumor of the bone (osteoclastoma) was diagnosed. No bony involvement was apparent either operatively, microscopically, or on preoperative computed tomographic scans. The neoplasm has not recurred in a 3-year follow-up. In addition to the fact that osteoclastoma complicating PBD is rare, the extraskeletal origin of the tumor is a matter of interest and can be tentatively explained by an unusually powerful systemic stimulus acting on circulating osteoclast precursors.

Original languageEnglish
Pages (from-to)1527-1531
Number of pages5
JournalHuman Pathology
Volume31
Issue number12
DOIs
Publication statusPublished - 2000

Keywords

  • Orbit
  • Osteoclastoma
  • Paget's disease
  • Soft tissue

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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