Organization of α-globin genes in Hb Hasharon (α 47asp→his) carriers

B. Giglioni, P. Comi, R. Taramelli, S. Ottolenghi, M. A. Ciocca-Vasino, C. Anè, M. D. Cappellini, A. M. Gianni

Research output: Contribution to journalArticlepeer-review


Restriction enzymes analysis of the DNA from two unrelated Italian families with Hb Hasharon, a variant Hb (α 47asp→his) frequently occurring in the Polesine area in Italy, indicates that this variant is associated to an α globin gene deletion. The α(Hash) genotype most likely results from a mutation on an α thal 2 genotype.

Original languageEnglish
Pages (from-to)1145-1149
Number of pages5
Issue number6
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Hematology


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