Oronasal mask versus helmet in acute hypercapnic respiratory failure

Lara Pisani, Chiara Mega, Rosanna Vaschetto, Andrea Bellone, Raffaele Scala, Roberto Cosentini, Muriel Musti, Manuela Del Forno, Mario Grassi, Luca Fasano, Paolo Navalesi, Stefano Nava

Research output: Contribution to journalArticlepeer-review


The choice of the interface for noninvasive ventilation (NIV) is a key factor in NIV success. We hypothesised that a new helmet specifically design to improve performance in hypercapnic patients would be clinically equivalent to a standard oronasal mask. In a multicentre, short-term, physiological, randomised trial in chronic obstructive pulmonary disease patients facing an acute hypercapnic respiratory failure episode, we compared the changes in arterial blood gases (ABGs) and tolerance score obtained using the helmet or mask, and, as secondary end-points, dyspnoea, vital signs, early NIV discontinuation and rate of intubation. 80 patients were randomly assigned to receive NIV either with the helmet (n=39) or mask (n=41), using an intensive care unit ventilator. Compared with baseline, in the first 6 h, NIV improved ABGs, dyspnoea and respiratory rate (p

Original languageEnglish
Pages (from-to)691-699
Number of pages9
JournalEuropean Respiratory Journal
Issue number3
Publication statusPublished - Mar 1 2015

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Medicine(all)


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