Osseointegration of endosseous ceramic implants after postoperative low-power laser stimulation: An in vivo comparative study

Gaetano A. Guzzardella, Paola Torricelli, Nicolà Nicoli-Aldini, Roberto Giardino

Research output: Contribution to journalArticle


Stimulation with low-power laser (LPL) can enhance bone repair as reported in experimental studies on bone defects and fracture healing. Little data exist concerning the use of LPL postoperative stimulation to improve osseointegration of endosseous implants in orthopaedic and dental surgery. An in vivo model was used for the present study to evaluate whether Ga-Al-As (780 nm) LPL stimulation can improve biomaterial osseointegration. After drilling holes, cylindrical implants of hydroxyapatite (HA) were placed into both distal femurs of 12 rabbits. From postoperative day 1 and for 5 consecutive days, the left femurs of all rabbits were submitted to LPL treatment (LPL group) with the following parameters: 300 J/cm 2, 1 W, 300Hz, pulsating emission, 10 min. The right femurs were sham-treated (control group). Three and 6 weeks after implantation, histomorphometric and microhardness measurements were taken. A higher affinity index was observed at the HA-bone interface in the LPL group at 3 (P

Original languageEnglish
Pages (from-to)226-232
Number of pages7
JournalClinical Oral Implants Research
Issue number2
Publication statusPublished - Apr 2003



  • Biomaterial
  • Bone implant
  • Low-power laser
  • Osseointegration

ASJC Scopus subject areas

  • Dentistry(all)

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