Osteoblast growth and functions in porous degradable synthetic matrices for bone repair: A preliminary study

G. Ciapetti, N. Baldini, L. Savarino, S. Pagani, D. Martini, L. Ambrosio, A. Giunti

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Large bone defects can be repaired only when the bone substitute is available in proper amount. Engineered bone seems a promising approach, but a number of variables have to be set before any conclusion is drawn. Poty-caprolactone-based polymers, with different porosity and-HA or +HA particles, have been tested in vitro using osteoblast-like Saos2 cells. Preliminary results show that the polymers, though degrading in the medium, have a positive interaction with cells, as they support cell growth and functions.

Original languageEnglish
Title of host publicationProceedings of the IEEE-EMBS Special Topic Conference on Molecular, Cellular and Tissue Engineering, MCTE 2002
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages48-49
Number of pages2
ISBN (Print)0780375572, 9780780375574
DOIs
Publication statusPublished - 2002
EventIEEE-EMBS Special Topic Conference on Molecular, Cellular and Tissue Engineering, MCTE 2002 - Genoa, Italy
Duration: Jun 6 2002Jun 9 2002

Other

OtherIEEE-EMBS Special Topic Conference on Molecular, Cellular and Tissue Engineering, MCTE 2002
CountryItaly
CityGenoa
Period6/6/026/9/02

Keywords

  • Biodegradation
  • Osteoblasts-bone
  • Polymers

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering
  • Biotechnology

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    Ciapetti, G., Baldini, N., Savarino, L., Pagani, S., Martini, D., Ambrosio, L., & Giunti, A. (2002). Osteoblast growth and functions in porous degradable synthetic matrices for bone repair: A preliminary study. In Proceedings of the IEEE-EMBS Special Topic Conference on Molecular, Cellular and Tissue Engineering, MCTE 2002 (pp. 48-49). [1174997] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MCTE.2002.1174997