Abstract
Osteointegration of yttria stabilised tetragonal zirconia (YSTZ), either coated with bioactive glass named RKKP bioglaze® (RKKP®) or uncoated, was evaluated in an animal model. RKKP®-coated and uncoated (controls) YSTZ cylinders were implanted in the distal femoral epiphyses of 14 Sprague Dawley rats under general anaesthesia. At the experimental times of 30 and 60 days after sacrifice, histomorphometry and SEM microanalysis were performed on methylmethacrylate-embedded undecalcified sections to determine the osteointegration rate. At 30 days, a significantly higher affinity index was demonstrated in vivo by histomorphometric evaluation in RKKP®-coated versus uncoated YSTZ implants (p
Original language | English |
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Pages (from-to) | 3833-3841 |
Number of pages | 9 |
Journal | Biomaterials |
Volume | 23 |
Issue number | 18 |
DOIs | |
Publication status | Published - 2002 |
Keywords
- Bioactive glass
- Ceramics
- Osteointegration
- Zirconia
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Biomedical Engineering