Osteointegration of bioactive glass-coated zirconia in healthy bone: An in vivo evaluation

V. Stanic; N. Nicoli Aldini; M. Fini; G. Giavaresi; R. Giardino; A. Krajewski; A. Ravaglioli; M. Mazzocchi; B. Dubini; M. G. Ponzi Bossi; F. Rustichelli

doi:10.1016/S0142-9612(02)00119-9

Osteointegration of bioactive glass-coated zirconia in healthy bone: An in vivo evaluation

V. Stanic, N. Nicoli Aldini, M. Fini, G. Giavaresi, R. Giardino, A. Krajewski, A. Ravaglioli, M. Mazzocchi, B. Dubini, M. G. Ponzi Bossi, F. Rustichelli

Istituti Ortopedici Rizzoli

Research output: Contribution to journal › Article › peer-review

Abstract

Osteointegration of yttria stabilised tetragonal zirconia (YSTZ), either coated with bioactive glass named RKKP bioglaze® (RKKP®) or uncoated, was evaluated in an animal model. RKKP®-coated and uncoated (controls) YSTZ cylinders were implanted in the distal femoral epiphyses of 14 Sprague Dawley rats under general anaesthesia. At the experimental times of 30 and 60 days after sacrifice, histomorphometry and SEM microanalysis were performed on methylmethacrylate-embedded undecalcified sections to determine the osteointegration rate. At 30 days, a significantly higher affinity index was demonstrated in vivo by histomorphometric evaluation in RKKP®-coated versus uncoated YSTZ implants (p

Original language	English
Pages (from-to)	3833-3841
Number of pages	9
Journal	Biomaterials
Volume	23
Issue number	18
DOIs	https://doi.org/10.1016/S0142-9612(02)00119-9
Publication status	Published - 2002

Keywords

Bioactive glass
Ceramics
Osteointegration
Zirconia

ASJC Scopus subject areas

Biotechnology
Bioengineering
Biomedical Engineering

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10.1016/S0142-9612(02)00119-9

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Osteointegration of bioactive glass-coated zirconia in healthy bone : An in vivo evaluation. / Stanic, V.; Nicoli Aldini, N.; Fini, M.; Giavaresi, G.; Giardino, R.; Krajewski, A.; Ravaglioli, A.; Mazzocchi, M.; Dubini, B.; Ponzi Bossi, M. G.; Rustichelli, F.

In: Biomaterials, Vol. 23, No. 18, 2002, p. 3833-3841.

Research output: Contribution to journal › Article › peer-review

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abstract = "Osteointegration of yttria stabilised tetragonal zirconia (YSTZ), either coated with bioactive glass named RKKP bioglaze{\textregistered} (RKKP{\textregistered}) or uncoated, was evaluated in an animal model. RKKP{\textregistered}-coated and uncoated (controls) YSTZ cylinders were implanted in the distal femoral epiphyses of 14 Sprague Dawley rats under general anaesthesia. At the experimental times of 30 and 60 days after sacrifice, histomorphometry and SEM microanalysis were performed on methylmethacrylate-embedded undecalcified sections to determine the osteointegration rate. At 30 days, a significantly higher affinity index was demonstrated in vivo by histomorphometric evaluation in RKKP{\textregistered}-coated versus uncoated YSTZ implants (p",

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AU - Stanic, V.

AU - Nicoli Aldini, N.

AU - Fini, M.

AU - Giavaresi, G.

AU - Giardino, R.

AU - Krajewski, A.

AU - Ravaglioli, A.

AU - Mazzocchi, M.

AU - Dubini, B.

AU - Ponzi Bossi, M. G.

AU - Rustichelli, F.

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AB - Osteointegration of yttria stabilised tetragonal zirconia (YSTZ), either coated with bioactive glass named RKKP bioglaze® (RKKP®) or uncoated, was evaluated in an animal model. RKKP®-coated and uncoated (controls) YSTZ cylinders were implanted in the distal femoral epiphyses of 14 Sprague Dawley rats under general anaesthesia. At the experimental times of 30 and 60 days after sacrifice, histomorphometry and SEM microanalysis were performed on methylmethacrylate-embedded undecalcified sections to determine the osteointegration rate. At 30 days, a significantly higher affinity index was demonstrated in vivo by histomorphometric evaluation in RKKP®-coated versus uncoated YSTZ implants (p

KW - Bioactive glass

KW - Ceramics

KW - Osteointegration

KW - Zirconia

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JF - Biomaterials

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Osteointegration of bioactive glass-coated zirconia in healthy bone: An in vivo evaluation

Abstract

Keywords

ASJC Scopus subject areas

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