Abstract
This study was designed to evaluate the osteointegration of HA-coated and uncoated titanium screws in the cortical bone of long-term (24 months) ovariectomized sheep (OVX group) compared to sham-aged sheep (Control group). At 12 weeks after implantation, the screws were tested biomechanically (extraction torque) and histomorphometrically (affinity index: AI) in both femoral and tibial diaphyses. Cancellous bone status was assessed by iliac crest biopsy. BMD of the L5 vertebra and a histomorphological study of the femoral and tibial shafts were performed to acquire data on cortical bone. A significant difference was found between the OVX and Control groups for BMD (p
| Original language | English |
|---|---|
| Pages (from-to) | 1017-1023 |
| Number of pages | 7 |
| Journal | Biomaterials |
| Volume | 23 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Feb 15 2002 |
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Keywords
- Hydroxyapatite
- Osteointegration
- Osteoporosis
- Ovariectomy
- Sheep
- Titanium
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Biomedical Engineering
Cite this
Osteointegration of hydroxyapatite-coated and uncoated titanium screws in long-term ovariectomized sheep. / Rocca, Michele; Fini, Milena; Giavaresi, Gianluca; Nicoli Aldini, Nicolò; Giardino, Roberto.
In: Biomaterials, Vol. 23, No. 4, 15.02.2002, p. 1017-1023.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Osteointegration of hydroxyapatite-coated and uncoated titanium screws in long-term ovariectomized sheep
AU - Rocca, Michele
AU - Fini, Milena
AU - Giavaresi, Gianluca
AU - Nicoli Aldini, Nicolò
AU - Giardino, Roberto
PY - 2002/2/15
Y1 - 2002/2/15
N2 - This study was designed to evaluate the osteointegration of HA-coated and uncoated titanium screws in the cortical bone of long-term (24 months) ovariectomized sheep (OVX group) compared to sham-aged sheep (Control group). At 12 weeks after implantation, the screws were tested biomechanically (extraction torque) and histomorphometrically (affinity index: AI) in both femoral and tibial diaphyses. Cancellous bone status was assessed by iliac crest biopsy. BMD of the L5 vertebra and a histomorphological study of the femoral and tibial shafts were performed to acquire data on cortical bone. A significant difference was found between the OVX and Control groups for BMD (p
AB - This study was designed to evaluate the osteointegration of HA-coated and uncoated titanium screws in the cortical bone of long-term (24 months) ovariectomized sheep (OVX group) compared to sham-aged sheep (Control group). At 12 weeks after implantation, the screws were tested biomechanically (extraction torque) and histomorphometrically (affinity index: AI) in both femoral and tibial diaphyses. Cancellous bone status was assessed by iliac crest biopsy. BMD of the L5 vertebra and a histomorphological study of the femoral and tibial shafts were performed to acquire data on cortical bone. A significant difference was found between the OVX and Control groups for BMD (p
KW - Hydroxyapatite
KW - Osteointegration
KW - Osteoporosis
KW - Ovariectomy
KW - Sheep
KW - Titanium
UR - http://www.scopus.com/inward/record.url?scp=0037082744&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037082744&partnerID=8YFLogxK
U2 - 10.1016/S0142-9612(01)00213-7
DO - 10.1016/S0142-9612(01)00213-7
M3 - Article
C2 - 11791904
AN - SCOPUS:0037082744
VL - 23
SP - 1017
EP - 1023
JO - Biomaterials
JF - Biomaterials
SN - 0142-9612
IS - 4
ER -