Osteolysis in chronic myeloid leukemia

G. Lambertenghi-Deliliers, D. Castagnone, F. Porro, A. Cortelezzi

Research output: Contribution to journalArticlepeer-review


Four patients affected by chronic myeloid lekemia who developed osteolytic lesions in the course of the disease are described. According to the literature, the appearance of these alterations seems to signify an unfavorable prognosis, since they occur slightly before or even at the same time as the blastic transformation of the disease. However, in one case bone biopsy showed a metastasis of a solid tumor, emphasizing the importance of this procedure in order to give a more precise clinical evaluation, both diagnostic and therapeutic.

Original languageEnglish
Pages (from-to)175-181
Number of pages7
Issue number2
Publication statusPublished - 1978

ASJC Scopus subject areas

  • Cancer Research


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