Osteonecrosis of the hip after short courses of oral and inhaled steroids in a child with an increased number of glucocorticoid receptors

Ilenia Drigo; Alessia Saccari; Egidio Barbi; Fiora Bartoli; Giuliana Decorti; Alessandro Ventura

doi:10.1007/s00431-006-0197-x

Osteonecrosis of the hip after short courses of oral and inhaled steroids in a child with an increased number of glucocorticoid receptors

Ilenia Drigo, Alessia Saccari, Egidio Barbi, Fiora Bartoli, Giuliana Decorti, Alessandro Ventura

IRCCS pediatrico Burlo Garofolo

Research output: Contribution to journal › Article › peer-review

Abstract

We report an unusual case of osteonecrosis of the femoral head associated with recurrent myopathy and bone abnormalities in a two-year-old girl, in whom symptoms occurred after a ten-day course of oral betamethasone for infectious wheezy bronchitis, and eventually recurred and were worsened by topical treatment; a hypersensitivity to glucocorticoids is hypothesised.

Original language	English
Pages (from-to)	913-915
Number of pages	3
Journal	European Journal of Pediatrics
Volume	165
Issue number	12
DOIs	https://doi.org/10.1007/s00431-006-0197-x
Publication status	Published - Dec 2006

Keywords

Glucocorticoid hypersensitivity
Glucocorticoid receptor
Infectious wheezing
Inhaled glucocorticoids
Osteonecrosis
Toxicity

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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abstract = "We report an unusual case of osteonecrosis of the femoral head associated with recurrent myopathy and bone abnormalities in a two-year-old girl, in whom symptoms occurred after a ten-day course of oral betamethasone for infectious wheezy bronchitis, and eventually recurred and were worsened by topical treatment; a hypersensitivity to glucocorticoids is hypothesised.",

keywords = "Glucocorticoid hypersensitivity, Glucocorticoid receptor, Infectious wheezing, Inhaled glucocorticoids, Osteonecrosis, Toxicity",

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AU - Drigo, Ilenia

AU - Saccari, Alessia

AU - Barbi, Egidio

AU - Bartoli, Fiora

AU - Decorti, Giuliana

AU - Ventura, Alessandro

PY - 2006/12

Y1 - 2006/12

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AB - We report an unusual case of osteonecrosis of the femoral head associated with recurrent myopathy and bone abnormalities in a two-year-old girl, in whom symptoms occurred after a ten-day course of oral betamethasone for infectious wheezy bronchitis, and eventually recurred and were worsened by topical treatment; a hypersensitivity to glucocorticoids is hypothesised.

KW - Glucocorticoid hypersensitivity

KW - Glucocorticoid receptor

KW - Infectious wheezing

KW - Inhaled glucocorticoids

KW - Osteonecrosis

KW - Toxicity

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Osteonecrosis of the hip after short courses of oral and inhaled steroids in a child with an increased number of glucocorticoid receptors

Abstract

Keywords

ASJC Scopus subject areas

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