L'osteoporosi maschile senile. Una criticità sanitaria emergente nella popolazione che invecchia

Translated title of the contribution: Osteoporosis in aged men. A significant problem for public health

Ivana Santi, M. Monti, C. I. Zanoni, F. Cetta

Research output: Contribution to journalArticlepeer-review

Abstract

One out of three osteoporotic fractures usually occur in men, but only few men at high risk of fracture are detected and treated. Fragility fractures represent the first clinical expression of osteoporosis (OP) in men, the most frequent sites being hip, vertebrae, humerus and distal forearm. Factors that may contribute to this lower fractures rate in men include the higher bone mass, with larger bone size achieved during growth, a better preservation of trabecular structure in adult life, lower risk of falls and a shorter life expectancy in men. Moreover the consequences of fractures in older men, both in terms of morbidity and mortality, appear to be more severe in men. The therapeutic decisions should be based on absolute fracture risk as estimated from age, Bone Mineral Density (BMD), fracture history, and additional clinical risk factors. In men, secondary osteoporosis deserves particular attention. The evidence base for the long-term efficacy and safety of therapies for osteoporosis in men, including the bone-active agents (bisphosphonates and teriparatide), is limited, so that they should be applied with discernment based on clinical judgement and careful estimation of fracture risk. Osteoporosis thus represents a significant threat for the health and wellbeing of the aging male population and a significant problem for public health.

Translated title of the contributionOsteoporosis in aged men. A significant problem for public health
Original languageItalian
Pages (from-to)33-41
Number of pages9
JournalGeriatric and Medical Intelligence
Volume19
Issue number1
Publication statusPublished - 2010

ASJC Scopus subject areas

  • Geriatrics and Gerontology

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