From 1984 until 1989 we treated 46 patients (22 males and 24 females) with 2 subsequent protocols of neoadjuvant chemotherapy for localized osteosarcoma of the extremities. The patients' mean age at diagnosis was 11 years and 6 months. Limb salvage was performed in 33 patients (72%), 8 (17%) had amputation and 5 (11%) had rotation plasty. The percentage of necrosis was good in 31 patients (67%), fair in 12 (26%) and poor in 3 (7%). At 3 and 7 years from diagnosis the actuarial survival rates are respectively 85% and 71%. At the same interval of time the actuarial continuous disease-free survival rates are 69% and 60%.
|Translated title of the contribution||Osteosarcoma of the extremities in childhood and adolescence: Evaluation of efficacy of the neoadjuvant treatment|
|Number of pages||8|
|Journal||Rivista Italiana di Pediatria|
|Publication status||Published - 1995|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health