Abstract
From 1984 until 1989 we treated 46 patients (22 males and 24 females) with 2 subsequent protocols of neoadjuvant chemotherapy for localized osteosarcoma of the extremities. The patients' mean age at diagnosis was 11 years and 6 months. Limb salvage was performed in 33 patients (72%), 8 (17%) had amputation and 5 (11%) had rotation plasty. The percentage of necrosis was good in 31 patients (67%), fair in 12 (26%) and poor in 3 (7%). At 3 and 7 years from diagnosis the actuarial survival rates are respectively 85% and 71%. At the same interval of time the actuarial continuous disease-free survival rates are 69% and 60%.
| Translated title of the contribution | Osteosarcoma of the extremities in childhood and adolescence: Evaluation of efficacy of the neoadjuvant treatment |
|---|---|
| Original language | Italian |
| Pages (from-to) | 849-856 |
| Number of pages | 8 |
| Journal | Rivista Italiana di Pediatria |
| Volume | 21 |
| Issue number | 6 |
| Publication status | Published - 1995 |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health