OSTEOSARCOMA DELLE ESTREMITA NELL'ETA EVOLUTIVA: VALUTAZIONE DELLA EFFICACIA DEL TRATTAMENTO NEOADIUVANTE

Translated title of the contribution: Osteosarcoma of the extremities in childhood and adolescence: Evaluation of efficacy of the neoadjuvant treatment

A. Brach Del Prever, L. Besenzon, M. Bianchi, P. L. Tarizzo, G. Bacci, P. Picci, E. Madon

Research output: Contribution to journalArticlepeer-review

Abstract

From 1984 until 1989 we treated 46 patients (22 males and 24 females) with 2 subsequent protocols of neoadjuvant chemotherapy for localized osteosarcoma of the extremities. The patients' mean age at diagnosis was 11 years and 6 months. Limb salvage was performed in 33 patients (72%), 8 (17%) had amputation and 5 (11%) had rotation plasty. The percentage of necrosis was good in 31 patients (67%), fair in 12 (26%) and poor in 3 (7%). At 3 and 7 years from diagnosis the actuarial survival rates are respectively 85% and 71%. At the same interval of time the actuarial continuous disease-free survival rates are 69% and 60%.

Translated title of the contributionOsteosarcoma of the extremities in childhood and adolescence: Evaluation of efficacy of the neoadjuvant treatment
Original languageItalian
Pages (from-to)849-856
Number of pages8
JournalRivista Italiana di Pediatria
Volume21
Issue number6
Publication statusPublished - 1995

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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